Results 81 to 90 of about 5,735,852 (363)

Data science for mental health: a UK perspective on a global challenge [PDF]

, 2016
Andrew M. McIntosh, Robert Stewart, Ann John, Daniel J. Smıth, Katrina A. S. Davis, Cathie Sudlow, Aiden Corvin, Kristin K. Nicodemus, David Kingdon, Lamiece Hassan, Matthew Hotopf, Stephen M. Lawrie, Tom C. Russ, John Geddes, Miranda Wolpert, Eva Wölbert, David J. Porteous   +16 more
openalex   +1 more source

Human rights in health systems frameworks: what is there, what is missing and why does it matter?

, 2012
Global initiatives and recent G8 commitments to health systems strengthening have brought increased attention to factors affecting health system performance.
Ahmed, Shahira, Bogecho, Dina, Ferguson, Laura, Gruskin, Sofia, Hanefeld, Johanna, Maccarthy, Sarah, Raad, Zyde, Steiner, Riley   +7 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Amplifying the global issue of hearing loss

The Lancet Global Health, 2022
The Lancet Global Health
doaj   +1 more source

Evolution of a transdisciplinary "One Medicine-One Health" approach to global health education at the University of California, Davis. [PDF]

, 2009
In today's world health events in one nation or geographic area often have repercussions for the health and well-being of populations beyond that region; sometimes even globally.
Clifford, Deana, Conrad, Patricia A, Mazet, Jonna A, Scott, Cheryl, Wilkes, Michael   +4 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Taking the neglected out of neglected tropical diseases

The Lancet Global Health, 2020
The Lancet Global Health
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Against the Odds: Making a Difference in Global Health [PDF]

, 2017
Against the Odds: Making a Difference in Global Health is a banner traveling exhibition highlighting the role of communities in improving health at home and all around the world.

core   +1 more source

Support for Global Health [PDF]

Science, 2010
As more nations struggle with stressed economies, aid to the developing world becomes increasingly vulnerable to governments' budgetary cuts. The industrialized world is recognizing that coordinating global development assistance is the most efficient way to maximize effectiveness and minimize duplication.
openaire   +2 more sources