Results 81 to 90 of about 2,604,946 (316)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Global disease detection : advancing the science of global public health [PDF]

open access: yes
Did You Know\ue2\u20ac\ua2 Three of the top 10 causes of death globally are from infectious diseases?\ue2\u20ac\ua2 Most of these deaths are occurring in low- and middle-income countries?\ue2\u20ac\ua2 About 2/3 of the world\ue2\u20ac\u2122s countries ...

core  

Doctors for Global Health Statement on Gaza

open access: yesSocial Medicine
We, Doctors for Global Health, write with a broken heart, this letter to publicly condemn the horrific atrocities ongoing in Gaza, which the  United Nations (UN) Special Rapporteur has stated that there are “reasonable grounds” to declare a ...
Doctors for Global Health
doaj  

Enhancing, and protecting, maternal and neonatal health care

open access: yesThe Lancet Global Health, 2021
The Lancet Global Health
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Global Health Impact Index: Promoting Global Health

open access: yesPLOS ONE, 2015
Millions of people cannot access essential medicines they need for deadly diseases like malaria, tuberculosis (TB) and HIV/AIDS. There is good information on the need for drugs for these diseases but until now, no global estimate of the impact drugs are having on this burden. This paper presents a model measuring companies' key malaria, TB and HIV/AIDS
openaire   +4 more sources

Global Health Security Agenda: Action Packages [PDF]

open access: yes
civil society to accelerate progress toward a world safe and secure from infectious disease threats; to promote global health security as an international priority; and to spur progress toward full implementation of the World Health Organization (WHO ...

core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Global health research helps save lives [PDF]

open access: yes
Issue title: Global health research helps save livesWelcome to 2009\ue2\u20ac\u2122s third quarter Global Health E-Brief, designed to inform readers about key global health activities at the Centers for Disease Control and Prevention (CDC).

core  

Financing for health: where there's a will…

open access: yesThe Lancet Global Health, 2016
The Lancet Global Health
doaj   +1 more source

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