Results 61 to 70 of about 254,442 (188)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Becoming data in education: the enactment of the homo oeconomicus through measuring

open access: yesCogent Education
This article examines how educational measurement instruments in Chile—specifically the School Vulnerability Index (SVI), The complementary questionnaires of the System for Measuring the Quality of Education in Chile (SIMCE), and the complementary ...
Valentina Riberi, Claudia Matus
doaj   +1 more source

The Hierarchy Solution to the LHC Inverse Problem

open access: yes, 2015
Supersymmetric (SUSY) models, even those described by relatively few parameters, generically allow many possible SUSY particle (sparticle) mass hierarchies.
Gainer, James S.   +2 more
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Systematic Study Of Leptonic Mixing In A Class Of SU_H(2) Models

open access: yes, 2006
We perform a systematic analysis of the PMNS matrices which arise when one assigns the three generations of leptons to the $2\oplus 1$ representation of a horizontal $SU_H(2)$ symmetry. This idea has been previously explored by Kuchimanchi and Mohapatra.
B. H. J. McKellar   +4 more
core   +1 more source

Using treemaps for variable selection in spatio-temporal visualisation [PDF]

open access: yes, 2008
We demonstrate and reflect upon the use of enhanced treemaps that incorporate spatial and temporal ordering for exploring a large multivariate spatio-temporal data set. The resulting data-dense views summarise and simultaneously present hundreds of space-
Dykes, J., Slingsby, A., Wood, J.
core   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

The Effect of Urban Land Use Changing on Green Area Neighborhoods No. 336 & 338 in Baghdad – Case Study

open access: yesJournal of Engineering, 2018
The role of the green areas lies in being one of the systems that plays the vital role in achieving the environmental dimension besides the socio-cultural body and the economic dimension in the hidden value of ecosystem services. However, many developing
Shireen Ihsan Khaza'al Hasson   +1 more
doaj   +1 more source

Addressing Racism and Its Deeply Entrenched Dynamics: A 21st Century Imperative

open access: yesHealth Equity, 2023
Throughout the world, extreme nationalism, racism, anti-Semitism, and other forms of ethnic and religious bias are sustained by an antiquated notion that the human family can be divided and ranked based on physical characteristics and ascribed traits ...
doaj   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

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