Results 111 to 120 of about 4,042,650 (303)
Turkish History Education JournalKüresel tarih yaklaşımı, modern dünyayı şekillendiren etkileşim ve bağlantıları anlamaya, bölünmüşlüğü önlemeye ve dünya inşasına dair belirli bir perspektif sunmaya yönelik bir yöntem olarak ortaya çıktı.
Bahri Ata, Abdurrahman Gülmez
doaj +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
World ecology and global environmental governance [PDF]
Environmental problems have always been part of our history, of life, and work. Yet the way in which environmental problems are perceived and politicized has changed: If it was at first chiefly local and regional environmental problems that were ...
Brühl, Tanja, Simonis, Udo E.
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History of Cervical Cancer and the Role of the Human Papillomavirus, 1960-2000 [PDF]
, 2009 Annotated and edited transcript of a Witness Seminar held on 13 May 2008. Introduction by Professor Anne M Johnson, Division of Population Health and Institute for Global Health, UCL.
Reynolds, LA, Tansey, EM
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
From Tell Ye Your Children to Dinner with Polpot: the challenges of globalizing Holocaust memories at Sweden’s Living History Forum [PDF]
, 2015 Established in 2003 as Europe’s first publically funded national educational authority on the Holocaust, tolerance, democracy and human rights, Sweden’s Living History Forum (LHF) lies at the intersection of global, national and local Holocaust ...
Allwork, Larissa
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