Results 51 to 60 of about 9,417,861 (245)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
An updated definition of global health
The most cited definition of global health, published in The Lancet in 2009, defines global health as "an area for study, research, and practice that places a priority on improving health and achieving equity in health for all people worldwide".
Waggett, Caryl E. +15 more
core +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Background Antimicrobial resistance (AMR) is one of the top ten global public health challenges. However, given the lack of a comprehensive assessment of worldwide AMR status, our objective is to develop a One Health-based system-wide evaluation tool on ...
Nan Zhou +14 more
doaj +1 more source
2016 Global Hunger Index: Africa edition
The 2016 Global Hunger Index Africa Edition is produced by the International Food Policy Research Institute (IFPRI), Concern Worldwide, and Welthungerhilfe in conjunction with NEPAD.
von Grebmer, Klaus; Bernstein, Jill; Nabarro, David; Prasai, Nilam; Amin, Shazia; Yohannes, Yisehac; Sonntag, Andrea; Patterson, Fraser; Towey, Olive; Thompson, Jennifer +1 more
core +1 more source
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
In Memoriam for Li Keqiang (1955—2023): The President China Could Have Had, But Never Did [PDF]
As we reflect on his life, we reflect on the opportunities that seemed within reach but ultimately remained elusive. Li Keqiang was a man who carried the hopes and aspirations of many, not only as a competent leader but also as someone who could have ...
IndraStra Global, Editorial Team
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

