Results 61 to 70 of about 589 (237)
Geochemistry, Geophysics, GeosystemsRates of seismicity in the Delaware Basin of Texas and New Mexico increased from 10 earthquakes per year of local magnitude (ML) 3.0 and above in 2017 to more than 185 in 2022, coincident with increasing oil and gas production and wastewater re‐injection
K. M. Smye +8 more
doaj +1 more source
The globalization of drug injecting* [PDF]
Addiction, 2004 A, Wodak, S, Sarkar, F, Mesquita
openaire +2 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Journal of Petroleum Exploration and Production TechnologyGreenhouse gases pose a significant threat to life on Earth by trapping infrared radiation, leading to global warming. In Bangladesh, carbon dioxide (CO2) emissions have surged by 40% from 2000 to 2020, primarily from the power industry and process ...
Md. Shakil Rahaman, Md. Ashraful Islam
doaj +1 more source
Is global warming injecting randomness into the climate system? [PDF]
Eos, Transactions American Geophysical Union, 2004 Data analyses and model simulations have recently indicated that as the planet is warming, the chance for extreme events increases. Karl et al.. [1995] examined precipitation records over the 20th century and showed that the high‐frequency (up to interannual) variability has increased.
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FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Injecting greater urgency into global tobacco control [PDF]
Tobacco Control, 2005 Keynote address at the Society for Research on Nicotine and Tobacco annual meeting, Prague, 21 March 2005 This year has begun well for tobacco control. One hundred and ninety two countries, all members of the World Health Organization, have solemnly pledged to rid the world of the death and disease trail caused by tobacco.
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Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source