Results 211 to 220 of about 7,366,248 (260)

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

Advanced Science, EarlyView.
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye, Jiamin Wu, Zixin Wu, Xi Liu, Jiajia Luo, Leyi Yang, Peng Shi   +6 more
wiley   +1 more source

Effects of Sodium-Glucose Cotransporter-2 Inhibitors on Left Ventricular Global Longitudinal Strain in Adults with Type 2 Diabetes Mellitus: A Systematic Review. [PDF]

J Clin Med
Dăniluc L, Dăniluc R, Benea A, Lazăr-Höcher AI, Virzob CRB, Popa MD, Susan R, Braha A, Apostol A, Sima A, Ali LH, Suhov L, Hutanu D, Ivan MV.   +13 more
europepmc   +1 more source

Disorder Driven Anisotropic Nonlinear Hall Effect in the Kagome Metal YbCo6Ge6 at Room Temperature

Advanced Science, EarlyView.
The intrinsic structural disorder and short‐range correlated motifs in the kagome metal YbCo6Ge6 constitute the primary mechanism for a robust and anisotropic nonlinear Hall effect (NLHE). This effect is sustained across a wide temperature range, achieving a nonlinear responsivity of up to ∼4.5 × 10−3 m/V at 70 K, higher than known disordered and ...
Qurat Ul Ain, Weiyao Zhao, Thanh Tung Huynh, Yuefeng Yin, Fang Tang, Yong Fang, Junlin Yan, Jacek Jasieniak, Timothy Petersen, Yang Liu, Nikhil V. Medhekar, Julie Karel   +11 more
wiley   +1 more source

Global Longitudinal Strain and Brain Natriuretic Peptide as Prognostic Biomarkers for Asymptomatic Severe Aortic Regurgitation With Preserved Ejection Fraction: Protocol for a Systematic Review and Meta-Analysis. [PDF]

JMIR Res Protoc
Kim MR, Shaikh T, Taylor S, Wang S, Goel V, DiCaro M, Khetarpal BK, Batra K.   +7 more
europepmc   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Global Longitudinal Strain for Prognostic Staging in Wild-Type Transthyretin Cardiac Amyloidosis. [PDF]

Circ Cardiovasc Imaging
Debonnaire P, L'Hoyes W, Donal E, Verheyen N, Vervloet D, Dujardin K, Pouleur AC, Dulgheru R, Sarli Issa V, Droogmans S, Jurcut R, Regeer M, Dupont M, Bondue A, Timmermans P, Bohyn A, Christiaen E, Wyseure N, Bezard M, Zach D, Schwegel N, Knapen R, Buytaert L, de Marneffe N, Adam R, Ajmone Marsan N, Tavernier R, Buysschaert I, Trenson S.   +28 more
europepmc   +1 more source

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Epicardial and Visceral Adipose Tissue and Global Longitudinal Strain: A Review of Cardiac Imaging Insights in Subclinical Myocardial Dysfunction. [PDF]

Nutrients
Vicardi M, Farzaneh-Far A, Fava C, Dalle Carbonare L, Romano S.   +4 more
europepmc   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Fully automated artificial intelligence-based echocardiographic analysis for global longitudinal strain monitoring and cancer therapy-related cardiac dysfunction detection in breast cancer patients. [PDF]

Eur Heart J Digit Health
Saijo Y, Zheng R, Okushi Y, Nomura Y, Hirata Y, Inoue H, Yamada H, Kusunose K, Sata M.   +8 more
europepmc   +1 more source