Results 281 to 290 of about 453,853 (394)

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Association between pre-procedural computed tomography angiography-based global longitudinal strain and outcomes in patients undergoing transcatheter aortic valve implantation. [PDF]

Quant Imaging Med Surg
Chen YC, Gao YF, Zhou Z, Bo KR, Song GY, Xu L.   +5 more
europepmc   +1 more source

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Subclinical Myocardial Dysfunction in Type 2 Diabetes Mellitus: Insights from Left Ventricular Diastolic Function and Global Longitudinal Strain Assessment. [PDF]

Med Sci (Basel)
Nghiem TP, Tran HM, Nguyen DNQ, Dao LT, Tran CC, Vo TM.   +5 more
europepmc   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Ratio of interventricular septal thickness to global longitudinal strain accurately identifies cardiac amyloidosis. [PDF]

Open Heart
Cao L, Hong GJ, Abiragi M, Le J, Tacon PR, Chiu IM, Patel J, Stern LK, Daluwatte C, Ouyang D, Ricchiuto P.   +10 more
europepmc   +1 more source

Global Longitudinal Strain May Be the One that Appropriately Identifies Candidates of ICD Implantation [PDF]

Mohammad Hossein Nikoo, Mohammad Reza Zarrabi, Alireza Moaref, Iman Razeghian‐Jahromi   +3 more
openalex   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

Revisiting the Prognostic Landscape of Hypertrophic Cardiomyopathy and Hypertension: The Critical Role of Left Ventricular Global Longitudinal Strain. [PDF]

Korean Circ J
Kim SR, Kim MN.
europepmc   +1 more source

Global Longitudinal Strain Imaging in Detection of Subclinical Left Ventricular Systolic Dysfunction in Patients with Asymptomatic Severe Aortic Stenosis

Arun Dinaraj, V.V. Radhakrishnan
openalex   +1 more source