Results 291 to 300 of about 453,853 (394)

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Reliability of left ventricular global longitudinal strain across acquisition and analysis techniques: a prospective comparative study. [PDF]

Eur Heart J Imaging Methods Pract
Gong F, Akhter N, Vaitenas I, Wodzinski B, Lancki N, Welty LJ, Maganti K.   +6 more
europepmc   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Global Longitudinal Strain Reduction With Apical Sparing in Cushing Syndrome-Related Heart Failure With Preserved Ejection Fraction (HFpEF): A Case Report. [PDF]

Cureus
Rachid A, Chaaban B, Mohammed M, Jibai A, Kazma H.   +4 more
europepmc   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Global Longitudinal Strain as a Prognostic Biomarker for Asymptomatic Moderate to Severe Aortic Regurgitation with Preserved Ejection Fraction: A Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Kim MR, Shaikh T, Taylor S, Wang S, Nguyen D, Khetarpal BK, Namazi A, Goel VS, Sagaribay R, Batra K.   +9 more
europepmc   +1 more source

THE RELATIONSHIP BETWEEN LONGITUDINAL FRACTIONAL SHORTENING AND DIASTOLIC FUNCTION IN INDIVIDUALS WITH HYPERTENSION AND THE GLOBAL LONGITUDINAL STRAIN VALUE IN PATIENTS WITH HYPERTENSIVE HYPERTROPHY FOR SUBCLINICAL LV DYSFUNCTION

-, KEERTHANA M P,ABINAYASRI K G, SANDHIYA R,SHERINE KARUNYA W,SURATHUL SAMRIN,SAMBATHKUMAR L,KISHORE KANNA
openalex   +1 more source

Subclinical cardiac dysfunction in idiopathic inflammatory myopathies: the role of global longitudinal strain [PDF]

Simone Romano, Andrea Sartorio, Chiara Dal Pont, Francesca Segatta, Marta Piazzola, F. Aldegheri, Riccardo Bixio, Ombretta Viapiana   +7 more
openalex   +1 more source

Biohybrid Tendons Enhance the Power‐to‐Weight Ratio and Modularity of Muscle‐Powered Robots

Advanced Science, EarlyView.
Biohybrid robots powered by skeletal muscle actuators are capable of dynamically adapting to environmental cues. This study takes inspiration from native muscle–tendon architecture by leveraging tough hydrogels as synthetic tendons for muscle actuators to enhance the power‐to‐weight ratio and modularity of biohybrid machines.
Nicolas Castro, Ronald Heisser, Maheera Bawa, Bastien Aymon, Sarah Wu, Annika Marschner, Sonika Kohli, Angel Bu, Laura Rosado, Martin Culpepper, Xuanhe Zhao, Ritu Raman   +11 more
wiley   +1 more source

Left ventricular global longitudinal strain and diagnostic yield of genetic testing in hypertrophic cardiomyopathy in a multicenter registry analysis. [PDF]

Sci Rep
Santner V, Höller V, Ungericht M, Schwegel N, Zach D, Tichy H, Waltl G, Belciug R, Wallner M, Gollmer J, Kolesnik E, Rainer PP, von Lewinski D, Ablasser K, Rudnik-Schöneborn S, Pölzl G, Heitzer E, Zirlik A, Verheyen N.   +18 more
europepmc   +1 more source