Results 301 to 310 of about 453,853 (394)

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

Speckle-Tracking Echocardiography in Dogs: Evaluating Imaging Parameters and Methodological Variability in Global Longitudinal Strain Assessment. [PDF]

Animals (Basel)
Mogensen JE, Bach MBT, Bay PG, Varlik T, Willesen JL, Gleerup CH, Koch J.   +6 more
europepmc   +1 more source

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

Advanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen   +18 more
wiley   +1 more source

Predictive Value of Baseline Left Ventricular Global Longitudinal Strain for Cardiac Dysfunction in Patients with Moderate to High Risk of Cancer Therapy-Related Cardiovascular Toxicity. [PDF]

Pharmaceuticals (Basel)
Borowiec A, Ozdowska P, Rosinska M, Zebrowska AM, Jasek S, Kotowicz B, Kosela-Paterczyk H, Lampka E, Nowecki Z, Walewski J.   +9 more
europepmc   +1 more source

Association between global longitudinal strain and occurrence of cardiovascular events among pediatric patients following high-dose cyclophosphamide chemotherapy: a prospective cohort study

Kai Mu, Jing Zhang, Hongyan Chen, Guoying Huang   +3 more
openalex   +1 more source

M-mode apical systolic excursion: A new and simple method to evaluate global left ventricular longitudinal strain

, 2015
José Amado, Fabián Islas, Islas Leopoldo Pérez de Isla, José Juan Gómez de Diego, José Agustín, Miguel Ángel García Fernández   +5 more
openalex   +1 more source

Left Ventricular Ejection Fraction and Global Longitudinal Strain

Journal of the American College of Cardiology, 2018
openaire   +1 more source

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

Improvement in global longitudinal strain following plasma cell-directed therapy is associated with long-term survival among patients with AL amyloidosis. [PDF]

Eur Heart J Open
Jang KH, Yu AF, Landau H, Ma X, Cheng RK, Mauer MS, Chuy KL, Lenihan D, Yang JC, Chen CL, Liu JE.   +10 more
europepmc   +1 more source

Influence of chloride-induced corrosion on tensile membrane behaviour of reinforced concrete slabs [PDF]

, 2015
Botte, Wouter, Caspeele, Robby, Taerwe, Luc   +2 more
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