Results 211 to 220 of about 192,650 (310)

Hyperpolarization of [1‐13C]Ketoisocaproate‐d2 by Reversible Exchange with Parahydrogen Enables Profiling of Branched‐Chain‐Amino‐Acid Metabolism in Cellulo and in Vivo

Advanced Science, EarlyView.
We report the fast generation of biocompatible solutions of highly 13C‐hyperpolarized (≈11%) partially‐deuterated ketoisocaproate within <6 min using spin‐lock‐induced crossing and reversible exchange with parahydrogen (SLIC‐SABRE). This enables rapid detection of branched‐chain‐amino‐acid transferase 1 (BCAT1) protein expression and investigation of ...
Stefan Petersen, Philipp R. Groß, Paul M. Schmidt, Henri de Maissin, Asitan Rittinger, Robert Willing, Adriana Sacristán‐Martín, Lisa Heß, Jule Koch, Sebastian Lucas, Maxim Zaitsev, Dominik von Elverfeldt, Martin Grashei, Franz Schilling, Jan‐Bernd Hövener, André F. Martins, Max von Delius, Thomas Reinheckel, Andreas B. Schmidt   +18 more
wiley   +1 more source

Bacterial contamination and prevalence of antibiotic-resistant <i>Escherichia coli</i> and <i>Salmonella</i> isolated from raw pork and chicken meat from slaughterhouses and retail markets in Kenya. [PDF]

Vet World
Nyanja MN, Mbindyo CM, Wanja DW, Ombui J, Peter GS, Kibegwa FM, Gitao GC, Kato CD.   +7 more
europepmc   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

Editorial: Standard employment enclaves, precarity and informality: explaining employment configurations in the global south. [PDF]

Front Sociol
Dingeldey I, Fechner H, Julián-Vejar D.
europepmc   +1 more source

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

Advanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding, Songpeng Jia, Ran Meng, Xuelei Wang, Xiongfei Wu, Weiliang Shen, Yibo Zhang, Junquan Zhu   +7 more
wiley   +1 more source

The AI Health Arms Race: A Critical Perspective on Big Tech and the Widening Global Health Equity Gap. [PDF]

J Multidiscip Healthc
Ahmed MM, Othman ZK.
europepmc   +1 more source

From Chatbots to Co‐Scientists: The Impact of Knowledge‐Generating AI (AI 4.0) on Healthcare and Research

Advanced Science, EarlyView.
This perspective contrasts the historical, linear progression of early AI with the dynamic, iterative nature of AI 4.0; and it describes the real‐world medical applications and the necessary evolution of laboratory infrastructure brought about by AI 4.0.
Weida Liu, Gary Peltz
wiley   +1 more source

Biomass carbon removal can help sustainable aviation fuels achieve on-time arrival. [PDF]

iScience
Langholtz M, Levy C, Field J, Sanchez DL, Christensen P, Murdoch L, Ugarte DT, Oyedeji O, Jacobson R, Zeng N, Heaton EA, Forsberg C, Sagues WJ.   +12 more
europepmc   +1 more source

All‐Solution‐Processed Perovskite Light‐Emitting Transistors Enabled by a Fully Organic Architecture

Advanced Electronic Materials, EarlyView.
Fully solution‐processed light‐emitting transistors based on CsPbBr3 perovskite nanocrystals (Pe‐LETs) are demonstrated using an all‐organic platform. By optimizing film formation and device integration, the Pe‐LETs achieve bright green emission with excellent color purity and a peak external quantum efficiency of 4.17 × 10−3 %, marking a step forward ...
Kelment Zahoaliaj, Alice Fappani, Francesca Pallini, Valentina Bellotti, Nicolò Quaresima, Margherita Bolognesi, Mario Prosa, Luca Beverina, Stefano Toffanin   +8 more
wiley   +1 more source

On the Role of Preprocessing and Memristor Dynamics in Reservoir Computing for Image Classification

Advanced Electronic Materials, EarlyView.
ABSTRACT Reservoir computing (RC) is an emerging recurrent neural network architecture that has attracted growing attention for its low training cost and modest hardware requirements. Memristor‐based circuits are particularly promising for RC, as their intrinsic dynamics can reduce network size and parameter overhead in tasks such as time‐series ...
Rishona Daniels, Duna Wattad, Ronny Ronen, David Saad, Shahar Kvatinsky   +4 more
wiley   +1 more source