Results 141 to 150 of about 7,989,093 (301)

Networks and global order

, 2018
Theoretical approach of networks in global ...
Orsini, Amandine, GEM authors’ workshop for GEM book Networks and the European Union: Threats and Opportunities of Complexity, Godet, Claire   +2 more
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Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

GLOBAL OPTIMIZATION METHODS [PDF]

Training a neural network is a difficult optimization problem because of numerous local minimums. Many global search algorithms have been used to train neural networks. However, local search algorithms are more efficient with computational resources, and
Brorsen, B. Wade, Hamm, Lonnie
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Breathe: global networks in respiratory disease. [PDF]

Breathe (Sheff), 2017
Riha RL.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Brexit and health security: why we need to protect our global networks. [PDF]

J Public Health Policy, 2019
Solomon D.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Extraction d’informations topographiques et hydrologiques à partir d’un modèle numérique de terrain - Cas pratique sur le MNT du projet Desert Networks

, 2019
Par Louis Manière, ingénieur d'étude, responsable de la création du SIG du projet Desert Networks (CNRS, HiSoMA, Lyon) L'un des objectifs du projet ERC Desert Networks est la compréhension et la reconstitution des itinéraires antiques qui ont permis ...
Desert Networks
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Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Penser global

, 2013
Le carnet de recherche "Penser global" accompagne la préparation, le déroulement et la valorisation du Colloque international organisé par la Fondation Maison des sciences de l'homme à l'occasion de son 50e anniversaire, du 15 au 17 mai 2013 à Paris.
Penser global
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