Results 101 to 110 of about 995,231 (341)
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
Global Attractivity of the Equilibrium of a Difference Equation: An Elementary Proof Assisted by Computer Algebra System [PDF]
arXiv, 2008 Let $p$ and $q$ be arbitrary positive numbers. It is shown that if $q < p$, then all solutions to the difference equation \tag{E} x_{n+1} = \frac{p+q x_n}{1+x_{n-1}}, \quad n=0,1,2,..., \quad x_{-1}>0, x_0>0 converge to the positive equilibrium $\overline{x} = {1/2}(q-1 + \sqrt{(q-1)^2 + 4 p})$. \medskip The above result, taken together with the 1993
arxiv
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
Vision-Based Georeferencing of GPR in Urban Areas
Sensors, 2016 Ground Penetrating Radar (GPR) surveying is widely used to gather accurate knowledge about the geometry and position of underground utilities. The sensor arrays need to be coupled to an accurate positioning system, like a geodetic-grade Global Navigation
Riccardo Barzaghi +3 more
doaj +1 more source
Optical Astrometry and the Global Positioning System [PDF]
, 1991 P. C. Kammeyer +2 more
openalex +1 more source
Technological Strategy of Using Global Positioning System: An Analysis [PDF]
IJEST Volume 1 Issue 1 2009 8-16, 2010 The Global Positioning System (GPS) is a U.S. space-based radionavigation system that provides reliable positioning, navigation, and timing services to civilian users on a continuous worldwide basis -- freely available to all. GPS provides specially coded satellite signals that can be processed in a GPS receiver, enabling the receiver to compute ...
arxiv
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Smartphone Global Positioning System-Based System to Assess Mobility in Health Research: Development, Accuracy, and Usability Study. [PDF]
JMIR Rehabil Assist Technol, 2023 Spang RP +5 more
europepmc +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source