Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Does global positioning system-based navigation dependency make your sense of direction poor? A psychological assessment and eye-tracking study. [PDF]
Front Psychol, 2022 Yan W +9 more
europepmc +1 more source
A turn-key Concept for active cancellation of Global Position System L3 Signal [PDF]
, 2010 Lou Nigra +6 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Relationship Between Life-Space Mobility and Health Characteristics in Older Adults Using Global Positioning System Watches. [PDF]
J Appl Gerontol, 2022 Chung J, Boyle J, Wheeler DC.
europepmc +1 more source
Extracting of Shoreline in Baltim Beach Using Remote Sensing and Global Positioning System (Gps) Techniques . (Dept. C ( Irrigation And Hydraulics ) ) [PDF]
, 2020 Bahaa El-Sharnouby +3 more
openalex +1 more source
Accuracy evaluation of a Low-Cost Differential Global Positioning System for mobile robotics [PDF]
, 2023 Christian Blesing +4 more
openalex +1 more source
Orbiter global positioning system design and Ku-band problems investigation, exhibit B, revision 1 [PDF]
The LinCom effort in supporting the JSC study of the use of the Global Positioning System (GPS) on the space shuttle and in Ku-band problem investigation is documented.
Braun, W. R., Chie, C. M.
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Physical Demands during the Game and Compensatory Training Session (MD + 1) in Elite Football Players Using Global Positioning System Device. [PDF]
Sensors (Basel), 2022 Calderón-Pellegrino G +6 more
europepmc +1 more source