Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia+20 more
wiley +1 more source
Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy
ABSTRACT Objective To evaluate the utility of smartwatch and smartphone‐based activity metrics for assessing disease severity and quality of life in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods In the electronic monitoring of disease activity in patients with CIDP (EMDA‐CIDP) trial, we performed a prospective ...
Lars Masanneck+15 more
wiley +1 more source
Life within a limited radius: Investigating activity space in women with a history of child abuse using global positioning system tracking. [PDF]
Friedmann F+11 more
europepmc +1 more source
Global Positioning System measurements of strain accumulation and slip transfer through the restraining bend along the Dead Sea fault system in Lebanon [PDF]
Francisco Gomez+9 more
openalex +1 more source
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó+17 more
wiley +1 more source
Image guided radiotherapy moving towards real time adaptive radiotherapy; global positioning system for radiotherapy? [PDF]
McNair H, Buijs M.
europepmc +1 more source
Global Positioning System Analysis of Physical Demands in Small and Large-Sided Games with Floaters and Official Matches in the Process of Return to Play in High Level Soccer Players. [PDF]
Lozano D+6 more
europepmc +1 more source
GLOBAL POSITIONING AND BRAKING SYSTEM [PDF]
openaire +1 more source