Results 51 to 60 of about 750,607 (308)

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Analysis of Multipath Changes in the Polish Permanent GNSS Stations Network

Remote Sensing
This study examines the influence of multipath errors on Global Navigation Satellite System (GNSS) measurements collected at ASG-EUPOS reference stations between 2010 and 2021.
Jacek Rapiński, Dariusz Tomaszewski, Renata Pelc-Mieczkowska   +2 more
doaj   +1 more source

PENERAPAN SISTEM PRESENSI MOBILE DENGAN MENGGUNAKAN SENSOR GPS (KLINIK PRATAMA X DI JEMBER)

Jurnal Nasional Pendidikan Teknik Informatika (JANAPATI), 2020
Perangkat dengan sensor sidik jari yang digunakan sebagai perangkat khusus untuk menangani presensi sangat rentan mengalami kerusakan dan susah untuk dikonfigurasikan di saat awal penggunaannya. Dengan penelitian ini, harapannya diperoleh suatu perangkat
Ely Mulyadi, Andis Trihariprasetya, I Gede Wiryawan   +2 more
doaj   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Error Model for Autonomous Global Positioning Method Using Polarized Sky Light and True North Measurement Instrument

Applied Sciences
Long-distance navigation requires global positioning methods to have complete autonomy, particularly when the Global Positioning System is unavailable.
Yinlong Wang, Jinshan Li, Yi Luo, Jinkui Chu   +3 more
doaj   +1 more source

THE GLOBAL OPTIMAL PLACEMENT OF BLE BEACON FOR LOCALIZATION BASED ON INDOOR MAP [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2018
Anchor Nodes in a localization system obviously play a crucial role in determining the system’s quality. Their placement directly affects the localization accuracy and their number directly impacts the total cost of the system.
L. Ruan, L. Ruan, L. Ruan, L. Zhang, L. Zhang, L. Zhang, F. Cheng, F. Cheng, F. Cheng, Y. Long, Y. Long, Y. Long   +11 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Ionospheric biases correction for coordinates derived from GPS single point positioning

Annals of Geophysics, 2005
Most GPS users employ low cost receivers. These receivers do not allow users to record the pseudorange that they observe, but the computed coordinates. This work presents an original and simple method to correct ionospheric biases introduced in
M. Herraiz, S. M. Radicella, C. Brunini, E. Mohíno Harris, M. Gende   +4 more
doaj   +1 more source