Results 81 to 90 of about 995,231 (341)

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

Global Stabilization of a Class of Partially Known Positive Systems [PDF]

open access: yesarXiv, 2006
In this report we deal with the problem of global output feedback stabilization of a class of $n$-dimensional nonlinear positive systems possessing a one-dimensional unknown, though measured, part. We first propose our main result, an output feedback control procedure, taking advantage of measurements of the uncertain part, able to globally stabilize ...
arxiv  

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Can We Prove Stability by Using a Positive Definite Function with Non Sign-Definite Derivative? [PDF]

open access: yesarXiv, 2009
Novel criteria for global asymptotic stability of nonlinear uncertain finite-dimensional systems are presented. The results are obtained by a combination of the "discretization approach" and the ideas contained in the proof of the original Matrosov's result.
arxiv  

Positional information trade-offs in boundary-driven reaction-diffusion systems [PDF]

open access: yesNew J. Phys. 27, 023034 (2025)
Individual components such as cells, particles, or agents within a larger system often require detailed understanding of their relative position to act accordingly, enabling the system as a whole to function in an organised and efficient manner. Through the concept of positional information, such components are able to specify their position in order ...
arxiv   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Correlation-sum-deviation ranging method for vehicular node based on IEEE 802.11p short preamble

open access: yesInternational Journal of Distributed Sensor Networks, 2016
Growth of the traffic flow and traffic accident has raised more and more demands on wireless communication and positioning technologies that can provide new services such as vehicle collision warning and traffic management.
Xuerong Cui   +4 more
doaj   +1 more source

Assessment of BeiDou-3 and Multi-GNSS Precise Point Positioning Performance

open access: yesSensors, 2019
With the launch of BDS-3 and Galileo new satellites, the BeiDou navigation satellite system (BDS) has developed from the regional to global system, and the Galileo constellation will consist of 26 satellites in space. Thus, BDS, GPS, GLONASS, and Galileo
Guoqiang Jiao   +4 more
doaj   +1 more source

Sub-homogeneous positive monotone systems are insensitive to heterogeneous time-varying delays [PDF]

open access: yesarXiv, 2014
We show that a sub-homogeneous positive monotone system with bounded heterogeneous time-varying delays is globally asymptotically stable if and only if the corresponding delay-free system is globally asymptotically stable. The proof is based on an extension of a delay-independent stability result for monotone systems under constant delays by Smith to ...
arxiv  

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

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