Results 81 to 90 of about 112,634 (261)

The challenge of greening global product chains: meeting both ends

Sustainable Development, 2005
AbstractGreening of product chains has come up as an important means to systematically improve the environmental performance of products from cradle to cradle in Europe and elsewhere. Some experience with inter‐firm co‐operation aiming at reducing the environmental impacts has been generated in recent years.
Vermeulen, W.J.V., Ras, P.J.
openaire   +3 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Productivity and Substitution Patterns in Global Value Chains

, 2018
Abstract Fragmentation of production is posing new challenges to the analysis and measurement of productivity. Traditional approaches focus on firms, industries, or countries as the unit of analysis. This chapter argues that studies of global value chains (GVCs) are needed in situations where production is fragmented across firms and ...
Timmer, Marcel P., Ye, X.
openaire   +3 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Global–Local Linkage Patterns of Guangdong’s Industries: Evidence from Multi-Scale Input–Output Network Analysis

Systems
Globalization has reorganized industrial spatial patterns, embedding regional economies into complex global production systems. However, the existing literature primarily focuses on the national level, leaving the “global-national-local” multi-scale ...
Lingxiao Mao, Yi Liu, Xiaoying Qian, Weishi Zhang, Chaoyu Zhang   +4 more
doaj   +1 more source

Circular Economy: Questions for Responsible Minerals, Additive Manufacturing and Recycling of Metals

Resources, 2014
The concept of the circular economy proposes new patterns of production, consumption and use, based on circular flows of resources. Under a scenario where there is a global shift towards the circular economy, this paper discusses the advent of two ...
Damien Giurco, Anna Littleboy, Thomas Boyle, Julian Fyfe, Stuart White   +4 more
doaj   +1 more source

Productivity Measurement in Global Value Chains

International Productivity Monitor, 2017
Increasing fragmentation of production is posing new challenges to the measurement of productivity. Traditional approaches focus on firms, industries or countries as the unit of analysis. In this article we argue that studies of global value chains (GVCs) are needed.
openaire   +2 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Polityka delokalizacji produkcji w Unii Europejskiej w warunkach strategicznej rywalizacji Chin i USA. W kierunku nowego kształtu globalnych łańcuchów wartości

Politeja
THE POLICY OF RELOCATING PRODUCTION IN THE EUROPEAN UNION IN THE CONTEXT OF THE STRATEGIC RIVALRY BETWEEN CHINA AND THE USA: TOWARD GLOBAL VALUE CHAINS TRANSFORMATION The policy of relocating production in the EU is a response to the challenges faced ...
Marek Świstak
doaj   +1 more source