Results 71 to 80 of about 220,642 (308)

Growing with global production sharing: The tale of Penang export hub

open access: yes, 2015
This article seeks to broaden our understanding of the phenomenon of global production sharing and to explore policy options for developing countries for engaging effectively in production networks, through a case study on the export production hub in ...
Athukorala, Premachandra
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

One Network, Three Systems: Misalignment of Institutional Logics in the Global Production Networks of Chinese Movies in the 1990s

open access: yes, 2017
Recent discussion on comparative capitalism and global production networks has shed light on the role of national political economies in global economic integration. This body of literature focuses predominantly on the structural conditions, at both the
Shin, KV
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Global Networks of Innovation

open access: yesRevista de Antropología Social, 2012
This essay aims to analyze global processes in the local. For this purpose, it presents the ethnography of one of the icons of globalization: De-territorialized production networks. In particular, complex and multiple processes through which global firms
Carmen Bueno Castellanos
doaj   +1 more source

The role of trade costs in global production networks : evidence from China's processing trade regime [PDF]

open access: yes
In a seminal contribution, Yi (2003) has shown that vertically specialized trade should be more sensitive to changes in trade costs than regular trade. Yet empirical evidenceof this remains remarkably scant.
Van Assche, Ari, Ma, Alyson C.
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The Internet's Effects on Global Production Networks: Challenges and Opportunities for Managing in Developing Asia [PDF]

open access: yes
Placing global production networks (GPN) on the Internet poses a fundamental challenge, but also creates new opportunities for managing in Developing Asia.
Dieter Ernst
core  

Extractive Processes, Global Production Networks and Inequalities [PDF]

open access: yes, 2015
In the context of an increasing economic integration and the rising importance of the Global South regarding global trade and companies, scholarly debates that try to grasp the shape of this increasingly integrated global economy addressed global ...
Radhuber, Isabella M.   +1 more
core   +1 more source

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