Results 121 to 130 of about 119,302 (260)

Hospital-Level Determinants of Mortality After Pancreas Surgery: A Global Infrastructure Analysis. [PDF]

open access: yesAnn Surg
Hidalgo Salinas C   +9 more
europepmc   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

open access: yesAdvanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho   +13 more
wiley   +1 more source

Dual‐Gene Edited Extracellular Vesicles Remodel the Redox Homeostasis to Inhibit Ferroptosis in Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is driven by ferroptosis of nucleus pulposus cells (NPCs) as a core pathological mechanism. Nucleus pulposus progenitor cells (NPPCs), exhibiting stem cell‐like properties, yield extracellular vesicles (PEVs) with high affinity for NPCs and enable targeted phenotypic regulation.
Jing Yan   +10 more
wiley   +1 more source

Correction: A narrative review of global inequities in access to uterine artery embolisation. [PDF]

open access: yesCVIR Endovasc
Lojo-Lendoiro S   +9 more
europepmc   +1 more source

AI‐Assisted Tumor Boundary Delineation via Targeted Ultrasmall Iron Oxide Nanoprobe for High‐Contrast HER2‐Positive Tumor Imaging

open access: yesAdvanced Science, EarlyView.
A novel targeted and pH‐responsive MRI contrast agent was integrated with a 3D nnU‐Net deep learning framework to enable accurate delineation of tumor boundary morphology in HER2‐positive breast cancer imaging. ABSTRACT Breast cancer continues to be a leading cause of cancer‐related mortality in women globally, where precise diagnosis and clear tumor ...
Jiaying Zheng   +7 more
wiley   +1 more source

Impaired Chaperone‐Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation

open access: yesAdvanced Science, EarlyView.
This graphical abstract illustrates how chaperone‐mediated autophagy (CMA) regulates intervertebral disc degeneration (IDD). Under normal homeostasis (B), CMA degrades cytoplasmic Midnolin (MIDN) to maintain proteostasis. Under inflammatory stress (A), impaired CMA leads to cytoplasmic MIDN accumulation.
Xianglong Chen   +9 more
wiley   +1 more source

Simulation Training and Peripheral Angioplasty Learning: Protocol of a Quasi-Experimental Evaluative Cross-Sectional Study. [PDF]

open access: yesJMIR Res Protoc
Hammami R   +12 more
europepmc   +1 more source

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