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Assessment of Skin in Patients With Systemic Sclerosis Using High‐Frequency Ultrasound and Shear Wave Elastography: A Comparative Study With Histology, Molecular, and Clinical Parameters

Arthritis Care &Research, EarlyView.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai, Filemon Tan, Minghua Wu, Jeffery L. Browning, Samuel Theodore, Meng Zhang, Brian Skaug, Harshdeep Singh Chawla, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin, Maureen Mayes, Shervin Assassi   +12 more
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Global sensitivity analysis in inventory management

International Journal of Production Economics, 2007
Abstract This paper deals with the sensitivity analysis (SA) of inventory management models when uncertainty in the input parameters is given full consideration. We make use of Sobol’ function and variance decomposition method for determining the most influential parameters on the model output. We first illustrate the method by means of an analytical
BORGONOVO, EMANUELE, PECCATI, LORENZO
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Global Sensitivity Analysis

Operations Research, 1995
In applications of operations research models, decision makers must assess the sensitivity of outputs to imprecise values for some of the model's parameters. Existing analytic approaches for classic optimization models rely heavily on duality properties for assessing the impact of local parameter variations, parametric programming for examining ...
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Global Sensitivity Analysis via Optimal Transport

Management Science
We examine the construction of variable importance measures for multivariate responses using the theory of optimal transport. We start with the classical optimal transport formulation. We show that the resulting sensitivity indices are well-defined under input dependence, are equal to zero under statistical independence, and are maximal under fully ...
Borgonovo, Emanuele, Figalli, Alessio, Plischke, Elmar, Savaré, Giuseppe   +3 more
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Global nonlinear sensitivity analysis using walsh functions

Journal of Computational Physics, 1981
Abstract A new global nonlinear sensitivity analysis method is developed to investigate the sensitivity of solutions of mathematical models to large uncertainties in the parameters of the model. The method is exact for discrete models where the parameter variation is intrinsically two valued, and exact for continuous models where a two valued ...
Pierce, T. H., Cukier, R. I.
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Global sensitivity analysis in dynamic metabolic networks

Computers & Chemical Engineering, 2009
Abstract In this work, we have performed global sensitivity analysis on a large-scale dynamic metabolic network through variance-based techniques. Time profiles for sensitivity indices have been calculated for each parameter, based on Sobol’ approach (2001) .
Jimena Di Maggio, Juan C. Diaz Ricci, M. Soledad Diaz   +2 more
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Global Sensitivity Analysis for ABS

2012
In the previous chapter, we looked at the ratings variability due to model choice and parameter values. In the present chapter, we are going to investigate the ratings parameter sensitivity further by applying global sensitivity analysis techniques. Sensitivity analysis is a powerful methodology for analyzing how the uncertainty in the output can be ...
Francesca Campolongo, Henrik Jönsson, Wim Schoutens   +2 more
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Global Sensitivity Analysis

2017
After completing an uncertainty analysis , the next step is a global sensitivity analysis .
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Global Optimization and Sensitivity Analysis

Nuclear Science and Engineering, 1990
A new direction for the analysis of nonlinear models of nuclear systems is suggested to overcome fundamental limitations of sensitivity analysis and optimization methods currently prevalent in nucl...
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