Results 101 to 110 of about 4,928,378 (308)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The prevalence of selected risk factors for non-communicable diseases in Hargeisa, Somaliland: a cross-sectional study

BMC Public Health, 2019
Background Non-communicable diseases (NCDs), particularly cardiovascular diseases, diabetes, respiratory conditions and cancers, are the most common causes of morbidity and mortality globally.
Soheir H. Ahmed, Haakon E. Meyer, Marte K. Kjøllesdal, Niki Marjerrison, Ibrahimu Mdala, Aung Soe Htet, Espen Bjertness, Ahmed A. Madar   +7 more
doaj   +1 more source

Migration, ethnicity, racism and the COVID-19 pandemic: A conference marking the launch of a new Global Society. [PDF]

Public Health Pract (Oxf), 2021
Gruer L, Agyemang C, Bhopal R, Chiarenza A, Krasnik A, Kumar B.   +5 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Urban-rural differences in the prevalence of non-communicable diseases risk factors among 25–74 years old citizens in Yangon Region, Myanmar: a cross sectional study

BMC Public Health, 2016
Background Recent societal and political reforms in Myanmar may upturn the socio-economy and, thus, contribute to the country’s health transition. Baseline data on urban-rural disparities in non-communicable disease (NCD) risk factors are not thoroughly ...
Aung Soe Htet, Marius B. Bjertness, Lhamo Y. Sherpa, Marte Karoline Kjøllesdal, Win Myint Oo, Haakon E. Meyer, Hein Stigum, Espen Bjertness   +7 more
doaj   +1 more source

Global Risks 2015, 10th Edition. [PDF]

, 2015
The 2015 edition of the Global Risks report completes a decade of highlighting the most significant long-term risks worldwide, drawing on the perspectives of experts and global decision-makers.

core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Robust, Recognizable and Legitimate: Strengthening India's Appliance Efficiency Standards and Labels Through Greater Civil Society Involvement [PDF]

, 2013
Residential use accounts for 14 percent of global energy consumption. Appliance standards alone could achieve 17 percent energy reductions in the residential sector.
Bharath Jairaj, Neelam Singh, Sarah Martin   +2 more
core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Leukopenia and thrombocytopenia in dengue patients: a cross-sectional study from a tertiary hospitals in Koshi Province, Nepal

BMC Infectious Diseases
Introduction Dengue fever remains a public health challenge in Nepal, with hematological abnormalities like leukopenia and thrombocytopenia often observed.
Birendra Prasad Gupta, Surendra Uranw, Vivek Prasad Gupta, Elisha Deuba, Ajay Kumar Sah, Santosh Chaudhary, Chandramani Wagle   +6 more
doaj   +1 more source