Results 251 to 260 of about 947,098 (315)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Happiness Measured by a Single Item: Psychometric Evaluation of the Arabic Version of Fordyce Global Happiness Scale Among University Students and Mothers of Children With Intellectual Disabilities. [PDF]

Int J Methods Psychiatr Res
Ali AM, Al-Dossary SA, Fekih-Romdhane F, Atout M, Fakhrou A, Suliman MMH, Gaballa ASM, Zayed AMA, Hallit S, Laranjeira C.   +9 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Trait Emotional Intelligence in Childhood: Factorial Structure of the TEIQue-Child Form (CF) and Child Short Form (CSF). [PDF]

Behav Sci (Basel)
Mavroveli S, Petrides KV, Sanchez-Ruiz MJ.   +2 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Heterogeneous pathways to depressive and anxiety disorders: A cluster-based predictive study in a nationwide longitudinal cohort. [PDF]

Psychol Med
Chen C, Asai Y, Mochizuki Y, Hagiwara K, Okubo R, Nakagawa S, Tabuchi T.   +6 more
europepmc   +1 more source

Synthesis of sialylated human milk oligosaccharides by automated glycan assembly. [PDF]

Nat Commun
Kuo YT, Le Mai Hoang K, Seeberger PH.
europepmc   +1 more source

A novel parameter-free differentiable filled function for global optimization. [PDF]

Sci Rep
Chen G.
europepmc   +1 more source

Research on agricultural development issues based on comprehensive optimization strategy. [PDF]

Sci Rep
Dayou H, Jieyun LI, Ya W, Susu G, Xinran W, Xianchao W.   +5 more
europepmc   +1 more source

Global Calibration of a Collaborative Multi-Line-Scan Camera Measurement System. [PDF]

Sensors (Basel)
Xie Y, Wu N, Hou Y, Xu W, Yu J, Yin Z, Tan D.   +6 more
europepmc   +1 more source