Results 181 to 190 of about 730,247 (315)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Global stability and analysing the sensitivity of parameters of a multiple-susceptible population model of SARS-CoV-2 emphasising vaccination drive. [PDF]
Math Comput Simul, 2023 Prem Kumar R, Santra PK, Mahapatra GS.
europepmc +1 more source
Global error estimation in exponential integrators
, 2013 GLOBAL ERROR ESTIMATION IN EXPONENTIAL INTEGRATORS Auzinger W., Stolyarchuk R.R. For the numerical approximation of the solution :[0, ] n u T of semilinear stiff ODE systems ( u t) = Au(t) g(u(t)), u(0) given, (1) exponential integrators are widely ...
Auzinger, Winfried
core
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Injurious information propagation and its global stability considering activity and normalized recovering rate. [PDF]
PLoS One, 2021 Wang C, Wang Z, Pan Q.
europepmc +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Facilitating Trade and Global Financial Stability
In attempting to address uncertainties presented by the global economic climate through the era of possible shifting diplomatic relations – as well as changes in fiscal, monetary and foreign policies, this chapter seeks to highlight how amicable trade ...
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Global stability of an age-structured population model on several temporally variable patches. [PDF]
J Math Biol, 2021 Kozlov V +3 more
europepmc +1 more source