Results 221 to 230 of about 730,247 (315)

Globalizing and stabilizing global $\infty$-categories

We consider the question of cocompleting partially presentable parametrized $\infty$-categories in the sense of arXiv:2307.11001. As our main result we show that in certain cases one may compute such relative cocompletions via a very explicit formula given in terms of partially lax limits.
openaire   +2 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Global stability analysis and modelling onchocerciasis transmission dynamics with control measures. [PDF]

Infect Ecol Epidemiol
Konlan M, Abassawah Danquah B, Okyere E, Osman S, Amenyo Kessie J, Kobina Donkoh E.   +5 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Exploring local and global stability of COVID-19 through numerical schemes. [PDF]

Sci Rep
Xiao N, Xu H, Morani AH, Shokri A, Mukalazi H.   +4 more
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Task-level regulation enhances global stability of the simplest dynamic walker. [PDF]

J R Soc Interface, 2020
Patil NS, Dingwell JB, Cusumano JP.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Global stability for age-infection-structured human immunodeficiency virus model with heterogeneous transmission. [PDF]

Infect Dis Model
Zhang J, Wang L, Jin Z.
europepmc   +1 more source

Condition for Global Stability for a SEIR Model Incorporating Exogenous Reinfection and Primary Infection Mechanisms. [PDF]

Comput Math Methods Med, 2020
Wangari IM.
europepmc   +1 more source