Results 61 to 70 of about 4,995,991 (287)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

RNA quaternary structure and global symmetry [PDF]

open access: yesTrends in Biochemical Sciences, 2015
Many proteins associate into symmetric multisubunit complexes. Structural analyses suggested that, by contrast, virtually all RNAs with complex 3D structures function as asymmetric monomers. Recent crystal structures revealed that several biological RNAs exhibit global symmetry at the level of their tertiary and quaternary structures.
Christopher P, Jones   +1 more
openaire   +2 more sources

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Symmetries in physics: philosophical reflections [PDF]

open access: yes, 2002
This is the table of contents and first chapter of "Symmetries in physics: philosophical reflections", edited by Katherine Brading and Elena Castellani, Cambridge University Press, 2003.
Castellani, Elena   +4 more
core  

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Global Analysis by Hidden Symmetry [PDF]

open access: yes, 2017
Special volume in honor of Roger Howe on the occasion of his 70th ...
openaire   +2 more sources

Wormholes and global symmetries

open access: yesNuclear Physics B, 1989
Abstract We examine the effects that topological fluctuations in the structure of space-time have on the global U(1) symmetry of a scalar field theory. When the symmetry is not spontaneously broken we find wormhole solutions which break the U(1) symmetry despite the fact that they have infinite euclidean action.
L.F. Abbott, Mark B. Wise
openaire   +1 more source

Breaking conditional symmetry in automated constraint modelling with CONJURE [PDF]

open access: yes, 2014
This work was supported by UK EPSRC EP/K015745/1. Jefferson is supported by a Royal Society University Research Fellowship.Many constraint problems contain symmetry, which can lead to redundant search.
Gent, Ian   +8 more
core   +1 more source

vikraman/popl22-symmetries-artifact: v0.1

open access: yes, 2021
Artifact for Symmetries in Reversible ...
Vikraman Choudhury, Jacek Karwowski
core   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

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