Results 141 to 150 of about 1,744,467 (339)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

AN EMPIRICAL ANALYSIS OF THE EFFECTS OF THE 2007-2008 FINANCIAL CRISIS ON CHANGES IN THE VALUE CREATION OF FIRMS IN INDIVIDUAL INDUSTRIAL SECTORS [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2017
The main goal of this paper to answer the question: what are the factors that influence the value of the firm and how does the influencing force of these factors take shape in the various sectors of ten industries, in the light of the aftermath of the ...
Anita Kiss
doaj  

Networks in the shadow of markets and hierarchies : calling the shots in the visual effects industry [PDF]

open access: yes, 2009
The nature and organisation of creative industries and creative work has increasingly been at the centre of academic and policy debates in recent years.
Australian Research Council (Funder)   +3 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

EMPIRICAL EXAMINATION OF THE ROLE OF FACTORS AFFECTING THE VALUE OF FIRMS, IN RESPECT OF 8 YEARS [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2019
The goal of writing this article is to continue my previous empirical research (Kiss 2015). In the article written in 2015, I dealt with the question, what factors affect the value of the firm?
KISS Anita
doaj  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

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