Results 151 to 160 of about 1,744,467 (339)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Demand for Romanian automotive products in the global value chain [PDF]

open access: yesEastern Journal of European Studies, 2015
The study aims to assess the position of the Romanian automotive sector in intermediate and final production stages along global value chains. Data are collected from WIOD global input-output matrix (2011).
Alina Petronela NEGREA, Valentin COJANU
doaj  

Global Talentship: Toward a Decision Science Connecting Talent to Global Strategic Success [PDF]

open access: yes, 2002
It is widely accepted that global competitive advantage frequently requires managing such complex situations that traditional organization and job structures are simply insufficient.
Boudreau, John W.   +2 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Small farmers' access to high-value markets: what can we learn from the Malawi pigeopea value chain? [PDF]

open access: yes
Access to high-value markets remains one of the major challenges facing smallholder farmers in Africa. The paper applies a value chain analysis to the pigeonpea sub-sector in Malawi to determine ways of improving the access of small farmers to the global
Makoka, Donald
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Development Value Chains meet Business Supply Chains [PDF]

open access: yes, 2011
Value chain promotion is considered a key element of private sector development strategies and pro-poor growth. However, (value) chain concepts are rather complex and unclear.
Drost, S. (Sarah)   +2 more
core  

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