Results 121 to 130 of about 747,986 (295)
Global value chains, organizations and industrial work [PDF]
, 2015 Rather than focussing exclusively on a list of key figures in the sociology of industrial, organisational and work sociology, the chapter considers organisation and industrial work in the context of thematic periods in the development of capitalism since
Garvey, Brian, Stewart, Paul
core
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
The transformation of global value chains in the age of Covid-19 and Digitization. [PDF]
Procedia Comput Sci, 2022 Rösch AL, Härting RC, Gakharia S.
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Beyond the Farm Gate: Servicification, Global Value Chains, and Upgrading in Agricultural Exports
LandServicification—defined as the services value added embodied in goods—has been studied mainly in manufacturing, but its role in agricultural exports is less understood.
Hein Roelfsema, Christopher Findlay
doaj +1 more source
The rise and fall of countries in the global value chains. [PDF]
Sci Rep, 2022 Alves LGA +4 more
europepmc +1 more source
What happens when the market shifts to China ? the Gabon timber and Thai cassava value chains [PDF]
Rapid economic growth in China has boosted its demand for commodities. At the same time, many commodity sectors have experienced declining demand from high-income northern economies. This paper examines two hypotheses of the consequences of this shift in
Kaplinsky, Raphael +2 more
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
China, global value chains, and the middle-income trap
Business and PoliticsWhether China can avoid the middle-income trap has been the subject of extensive research. Currently classified as an upper middle-income country, China increasingly exhibits similar characteristics as countries currently experiencing the middle-income ...
Michael Murphree, Dan Breznitz
doaj +1 more source