Results 141 to 150 of about 5,140,187 (303)
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
Chapter 5: Global warming: The neglected supply side [PDF]
This chapter addresses one of the most long-term issues for mankind: global warming. The chapter points out that most existing analyses have neglected the supply side.
Hans-Werner Sinn +6 more
core
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini +12 more
wiley +1 more source
Most previous studies have reported a decrease in global tropical cyclone (TC) genesis frequency (TCGF) under anthropogenic warming. However, little attention has been drawn to the influence of sea surface temperature (SST) warming patterns on TCGF ...
Mingrui Xu, Ruifen Zhan, Jiuwei Zhao
doaj +1 more source
Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong +10 more
wiley +1 more source
Can subsidizing alternative energy technology development lead to faster global warming? [PDF]
Modelling global climate changes without taking account of the changes in resource markets can produce climate policy with perverse consequences. In even the simplest economic model of emissions of greenhouse gases, naïve policies that ignore markets can
Duncan, Roderick
core
Preventing a growing risk: Addressing the invasive potential of bioenergy feedstocks
Aviva Glaser, Patty Glick
doaj +1 more source
Global warming and the Sacramento-San Joaquin Delta
The likelihood of global warming and its potential consequences are major concerns to global climate researchers, government officials, and members of the public.
S Logan
doaj
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source

