Results 101 to 110 of about 2,226,999 (357)

A global analysis of controls on submarine-canyon geomorphology

open access: hybrid, 2022
Laura Bührig   +4 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

European Integration of Ukraine: Tool for Internal Reform, Source of Problems or Pass Ticket to EU Membership? [PDF]

open access: yesRomanian Journal of European Affairs, 2017
Despite the signing of the EU-Ukraine Association Agreement, there would seem to be no alternative to the European choice for Ukraine, given the current Russian aggression; there are different views on the objectives and results of the European ...
Oleh Poshedin, Maryna Chulaievska
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

In vitro Effects of Methanol Extracts of Korean Medicinal Fruits (Persimmon, Raspberry, Tomato) on Chicken Lymphocytes, Macrophages, and Tumor Cells

open access: yesThe Journal of Poultry Science, 2009
A variety of fruits have traditionally been used in Asian cultures to enhance resistance to diseases and treat cancers. However, limited information exists on the underlying mechanisms responsible for these effects.
Sung-Hyen Lee   +5 more
doaj   +1 more source

Globalization of Capital Markets [PDF]

open access: yes, 1997
Speech given at Session 1: The Global Capital Market: What\u27s Next. Richard Grasso spoke about the exciting changes that are transforming the global capital markets, particularly as seen from the perspective of 11 Wall Street.
Grasso, Richard A.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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