Results 151 to 160 of about 2,062,667 (361)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Politics Matter: Changes in Unionization Rates in Rich Countries, 1960-2010 [PDF]

open access: yes, 2011
Researchers have offered several explanations for the decline in unionization. Many emphasize that "globalization" and the technological advances embodied in the "new economy" have made unions obsolete.
Alexandra Mitukiewicz, John Schmitt
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

International ethics and globalization [PDF]

open access: yes, 2011
In the inherently anarchic international system the validity of moral principles is weakening. To overcome anarchy global governance is needed. It means efficient international institutions, but also pressures from the global civil society and the self ...
Boda, Zsolt
core  

Assessing mortgage default risk in full-recourse economies, with an application to the case of Chile

open access: yesLatin American Journal of Central Banking, 2020
This paper is aimed at finding individual and systemic determinants of housing default in a full-recourse economy. We propose an empirical strategy that accounts for rare events and choice-based sampling bias and estimates the contribution of ...
Diego Avanzini   +2 more
doaj  

Hochschild homology, global dimension, and truncated oriented cycles [PDF]

open access: yesarXiv, 2010
It is shown that a bounded quiver algebra having a 2-truncated oriented cycle is of infinite Hochschild homology dimension and global dimension, which generalizes a result of Solotar and Vigu\'{e}-Poirrier to nonlocal ungraded algebras having a 2-truncated oriented cycle of arbitrary length.
arxiv  

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