Results 111 to 120 of about 74,517 (259)
Ueber die Bildung des Leucinimids bei der peptischen und tryptischen Verdauung des Oxyhämoglobins resp. des Globins. [PDF]
S. N. Salaskin
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ABSTRACT Alzheimer's disease (AD) is one of the most common neurodegenerative disorders characterized by the accumulation of amyloid‐β (Aβ) peptide and phosphorylated tau protein in the brain. Despite intensive efforts, early diagnosis and monitoring of AD remain challenging due to the lack of reliable biomarkers that can detect the disease in its ...
Ceren Perihan Gonul+2 more
wiley +1 more source
Lentiviral addition of βT87Q-globin, a modified β-globin with an anti-sickling mutation, is currently being used in gene therapy trials for sickle cell disease (SCD) and β-thalassemia patients.
Selami Demirci+10 more
doaj
THE ANTIGENIC PROPERTIES OF GLOBIN CASEINATE [PDF]
Frédérick Gay, T. Brailsford Robertson
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The transcription factor RIP140 regulates interferon γ signaling in breast cancer
What's new? Interferon γ (IFNγ) is a key player in breast cancer, with the potential to induce apoptosis and to shift tumors into a dormant state. However, it also may promote carcinogenesis and angiogenesis. In this study, transcriptomic analysis identified the transcription factor RIP140 as a key regulator of IFNγ signaling in breast cancer.
Stéphan Jalaguier+9 more
wiley +1 more source
A major barrier to the clinical use of erythrocytes generated in vitro from pluripotent stem cells or cord blood progenitors is failure of these erythrocytes to express adult hemoglobin.
Kongtana Trakarnsanga+9 more
doaj +1 more source
ABSTRACT Posttraumatic osteoarthritis (PTOA) is a common sequela to anterior cruciate ligament (ACL) injury in humans and dogs. Identification of conserved targets between species may hasten biomarker identification and therapeutic development. To identify differentially regulated synovial fluid (SF) proteins in ACL injury, SF samples were collected ...
Sydney J. Womack+4 more
wiley +1 more source
Antenatal medication management for women with sickle‐cell disease: A systematic review
Abstract Background Improvements in sickle‐cell disease (SCD) treatment have led to an increasing number of individuals surviving to reproductive age. However, pregnancy in women with SCD carries a heightened risk of maternal and fetal complications.
Yaneve N. Fonge+10 more
wiley +1 more source
The repetition of homologous sequences in the polypetide chains of certain cytochromes and globins. [PDF]
C R Cantor, Thomas H. Jukes
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Abstract Infectious diseases impact numerous organisms. Knowledge of host‐pathogen interactions and host responses to infection is crucial for conservation and management. Obtaining this knowledge quickly is made increasingly possible by a variety of genomic approaches, yet, for many species the bottleneck to understanding this, remains access to ...
Allison K. Miller+7 more
wiley +1 more source