Results 121 to 130 of about 101,666 (347)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Revisiting the Globular Cluster Systems of NGC 3258 and NGC 3268

open access: yesGalaxies, 2017
We present a photometric study of NGC 3258 and NGC 3268 globular cluster systems (GCSs) with a wider spatial coverage than previous works. This allowed us to determine the extension of both GCSs, and obtain new values for their populations.
Juan Pablo Caso, Lilia Bassino
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Radial Color Gradient in a Globular Cluster 1. M68 [PDF]

open access: yesJournal of Astronomy and Space Sciences, 1990
Stars in M68 from the observed color-magnitude diagrams with CCD were integrated to find any radial gradient. The result shows that M68 has a slightly bluer core.
Sukyoung Yi, Mun-Suk Chun
doaj  

Globular Clusters in Nearby Galaxy Clusters [PDF]

open access: yes, 2006
6 pages, 4 figures, to appear in Proceedings of the ESO Workshop on "Extragalactic Globular Cluster Systems", ed. M. Kissler-Patig, Springer Verlag (2002)
openaire   +3 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

A supra-massive population of stellar-mass black holes in the globular cluster Palomar 5. [PDF]

open access: yesNat Astron, 2021
Gieles M   +4 more
europepmc   +1 more source

Star Cluster Candidates in M81

open access: yes, 2010
We present a catalog of extended objects in the vicinity of M81 based a set of 24 Hubble Space Telescope Advanced Camera for Surveys (ACS) Wide Field Camera (WFC) F814W (I-band) images. We have found 233 good globular cluster candidates; 92 candidate HII
Brian McLeod   +13 more
core   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

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