Results 141 to 150 of about 2,037,911 (340)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Population-dependent r-process Scatter in the Globular Cluster M15

The Astrophysical Journal Letters
Multiple populations, defined by correlations between light element abundances, are an almost ubiquitous property of globular clusters. On the other hand, dispersions among the heavy elements are limited to a few rare clusters. In this Letter, we present
Lauren E. Henderson, Roman Gerasimov, Evan N. Kirby   +2 more
doaj   +1 more source

Spectroscopy of Giant Stars in the Pyxis Globular Cluster [PDF]

, 2000
Christopher Palma, William E. Kunkel, Steven R. Majewski   +2 more
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Constraining the formation of NGC 1052-DF2 from its unusual globular cluster population [PDF]

, 2021
Sebastian Trujillo-Gomez, J. M. Diederik Kruijssen, Ben Keller, Marta Reina-Campos   +3 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Globular Cluster Formation [PDF]

, 2006
13 pages. Review to appear in "Extragalactic Globular Cluster Systems," ed. M.
openaire   +2 more sources

Surviving Tidal Tails Around the Milky Way Bulge Globular Cluster NGC 6355

The Astronomical Journal
We present results of the analysis of a set of images obtained in the field of the Milky Way bulge globular cluster NGC 6355 using the Dark Energy Camera, which is attached to the 4 m Blanco telescope of the Cerro-Tololo Interamerican Observatory.
Andrés E. Piatti
doaj   +1 more source

Eccentric black hole mergers via three-body interactions in young, globular, and nuclear star clusters [PDF]

, 2023
Marco Dall’Amico, Michela Mapelli, Stefano Torniamenti, Manuel Arca Sedda   +3 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source