Results 151 to 160 of about 2,066,093 (377)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Terzan 8: a Sagittarius-flavoured globular cluster [PDF]

open access: yes, 2013
Massive globular clusters (GCs) contain at least two generations of stars with slightly different ages and clearly distinct light element abundances. The Na-O anticorrelation is the best studied chemical signature of multiple stellar generations. Instead,
E. Carretta   +10 more
semanticscholar   +1 more source

A faint extended cluster in the outskirts of NGC 5128: evidence of a low mass accretion

open access: yes, 2010
We report the discovery of an extended globular cluster in a halo field in Centaurus A (NGC 5128), situated $\sim 38\kpc$ from the centre of that galaxy, imaged with the Advanced Camera for Surveys on board the Hubble Space Telescope.
Barmby   +51 more
core   +1 more source

Globular Cluster Microlensing: Globular Clusters as Microlensing Targets

open access: yes, 1997
6 pages, uses mn.sty, 2 ...
Gyuk, Geza, Holder, Gilbert P.
openaire   +2 more sources

Extragalactic globular clusters. II - The M31 globular cluster system

open access: yesThe Astrophysical Journal, 1991
Metallicities for 150 globular clusters associated with M31 are derived using the strengths of six absorption features in the cluster-integrated spectra. The properties of the M31 cluster system are very similar to those of the Galactic system. No dependence of metallicity on cluster luminosity is found.
Huchra, J. P.   +2 more
openaire   +3 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

THE NEXT GENERATION VIRGO CLUSTER SURVEY. VIII. THE SPATIAL DISTRIBUTION OF GLOBULAR CLUSTERS IN THE VIRGO CLUSTER [PDF]

open access: yes, 2014
We report on a large-scale study of the distribution of globular clusters (GCs) throughout the Virgo cluster, based on photometry from the Next Generation Virgo Cluster Survey (NGVS), a large imaging survey covering Virgo's primary subclusters (Virgo A =
P. Durrell   +23 more
semanticscholar   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

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