Results 151 to 160 of about 2,037,911 (340)

Is Earendel a Star Cluster?: Metal-poor Globular Cluster Progenitors at z ∼ 6

open access: yesThe Astrophysical Journal Letters
The strongly lensed z  ∼ 6 Sunrise galaxy offers an incredible opportunity to investigate star formation in the early Universe on parsec or smaller scales.
Massimo Pascale   +3 more
doaj   +1 more source

Metallicity of Globular Cluster M13 from VI CCD Photometry [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2000
From the VI images of M13, obtained by using 2K CCD camera and the BOAO 1.8m telescope, we derive the (V-I)-V CMD of M13. From the shapes of red giant branch, the magnitude of horizontal branch, and the giant branch bump on the constructed CMD, we ...
Young-Jong Sohn
doaj  

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

C-19 and Hot, Wide Star Streams

open access: yesThe Astrophysical Journal
The C-19 star stream has the abundance characteristics of an unusually metal-poor globular cluster but kinematically is uncharacteristically hot and wide for a cluster stream, having a line-of-sight velocity dispersion of 7  ±  2 km s ^−1 and a 1 σ width
Raymond G. Carlberg   +7 more
doaj   +1 more source

The origins of neutron-capture elements in globular cluster M22

open access: yesFrontiers in Astronomy and Space Sciences
IntroductionThe chemical abundances of metal poor (MP) stars in globular clusters provide valuable information for constraining their evolutionary scenarios.MethodsUsing both main r-process and weak r-process patterns, we fit the abundances of s-poor ...
Muhammad Zeshan Ashraf   +2 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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