Results 161 to 170 of about 2,037,911 (340)

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

F TURNOFF DISTRIBUTION IN THE GALACTIC HALO USING GLOBULAR CLUSTERS AS PROXIES [PDF]

open access: bronze, 2011
Matthew Newby   +4 more
openalex   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Improved Particle Spray Algorithm for Modeling Globular Cluster Streams

open access: yesThe Astrophysical Journal Supplement Series
Stellar streams that emerge from globular clusters (GCs) are thin stellar structures spread along the orbits of progenitor clusters. Numerical modeling of these streams is essential for understanding their interaction with the host galaxy's mass ...
Yingtian Chen   +3 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Constructing a Pristine View of Extended Globular Cluster Structure

open access: yesThe Astronomical Journal
Globular clusters (GCs) displaying extended structures are becoming increasingly ubiquitous in the Milky Way (MW). Despite their low surface brightness, which makes disentangling the true structure from the MW overwhelming difficult, the increasing ...
Pete B. Kuzma   +3 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

JWST Photometry of Globular Cluster Populations in MACS0417.5−1154

open access: yesThe Astrophysical Journal
Deep JWST imaging of the massive galaxy cluster MACS0417.5−1154, at redshift z = 0.443, reveals a huge population of globular clusters (GCs) and ultracompact dwarfs (UCDs) primarily distributed around its single central giant brightest cluster galaxy ...
William E. Harris   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy