Results 181 to 190 of about 2,066,093 (377)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The FAST Globular Cluster Pulsar Survey (GC FANS)

The Astrophysical Journal Supplement Series
By 2025 January, 60 pulsars were discovered by the Five-hundred-meter Aperture Spherical radio Telescope globular cluster (GC) pulsar survey (GC FANS), with spin periods spanning 1.98–3960.72 ms. Of these, 55 are millisecond pulsars (MSPs; P  
Yujie Lian, Zhichen Pan, Haiyan Zhang, Shuo Cao, P. C. C. Freire, Lei Qian, Ralph P. Eatough, Lijing Shao, Scott M. Ransom, Duncan R. Lorimer, Dejiang Yin, Yinfeng Dai, Kuo Liu, Lin Wang, Yujie Wang, Zhongli Zhang, Zhonghua Feng, Baoda Li, Minghui Li, Tong Liu, Yaowei Li, Bo Peng, Yu Pan, Yuxiao Wu, Liyun Zhang, Xingnan Zhang, Peng Jiang   +26 more
doaj   +1 more source

Studies in the Equilibrium of Globular Clusters (II) [PDF]

, 1956
R. v. d. R. Woolley, David Robertson
openalex   +1 more source

The Elliptical Galaxy formerly known as the Local Group: Merging the Globular Cluster Systems [PDF]

, 2000
Prompted by a new catalogue of M31 globular clusters, we have collected together individual metallicity values for globular clusters in the Local Group. Although we briefly describe the globular cluster systems of the individual Local Group galaxies, the
Barmby, Pauline, Forbes, Duncan A., Masters, Karen L., Minniti, Dante   +3 more
core   +3 more sources

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Radial Color Gradient in a Globular Cluster 1. M68 [PDF]

Journal of Astronomy and Space Sciences, 1990
Stars in M68 from the observed color-magnitude diagrams with CCD were integrated to find any radial gradient. The result shows that M68 has a slightly bluer core.
Sukyoung Yi, Mun-Suk Chun
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Population-dependent r-process Scatter in the Globular Cluster M15

The Astrophysical Journal Letters
Multiple populations, defined by correlations between light element abundances, are an almost ubiquitous property of globular clusters. On the other hand, dispersions among the heavy elements are limited to a few rare clusters. In this Letter, we present
Lauren E. Henderson, Roman Gerasimov, Evan N. Kirby   +2 more
doaj   +1 more source

Radial Velocities of Globular Clusters and Nebulae [PDF]

, 1935
S. W. Shiveshwarkar
openalex   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source