Results 81 to 90 of about 21,304 (244)
APOGEE physical properties of globular cluster tidal tails
Astronomy & AstrophysicsA recent model prediction claimed that there is a correlation between the formation scenarios of globular clusters (i.e., whether they formed in situ or in dark matter halos that were accreted into the Milky Way) and some properties of their tidal tails,
Piatti A. E.
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Nature, 1888 PHYSICAL aggregations of stars may be broadly divided into “globular” and “irregular” clusters. Although, as might have been expected, the line of demarcation between the two classes is by no means sharply drawn, each has its own marked peculiarities. We shall limit our attention, in the present article, to the first kind.
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
The FAST Globular Cluster Pulsar Survey (GC FANS)
The Astrophysical Journal Supplement SeriesBy 2025 January, 60 pulsars were discovered by the Five-hundred-meter Aperture Spherical radio Telescope globular cluster (GC) pulsar survey (GC FANS), with spin periods spanning 1.98–3960.72 ms. Of these, 55 are millisecond pulsars (MSPs; P
Yujie Lian +26 more
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Globular Cluster Formation [PDF]
, 2006 13 pages. Review to appear in "Extragalactic Globular Cluster Systems," ed. M.
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source