Results 131 to 140 of about 89,654 (284)
The Little Engines That Could? Globular clusters contribute significantly to reionization-era star formation. [PDF]
Mon Not R Astron Soc, 2018 Boylan-Kolchin M.
europepmc +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
The Astrophysical Journal LettersThe centers of massive elliptical galaxies exhibit a wide range in density profiles, from central cusps to resolved cores with order kiloparsec sizes.
Kyle Kremer +4 more
doaj +1 more source
Globular clusters in high-redshift dwarf galaxies: a case study from the Local Group. [PDF]
Mon Not R Astron Soc, 2018 Zick TO, Weisz DR, Boylan-Kolchin M.
europepmc +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
A Novel Technique for Long-term Timing of Redback Millisecond Pulsars
The Astrophysical JournalWe present timing solutions spanning nearly two decades for five redback (RB) systems found in globular clusters (GCs), created using a novel technique that effectively “isolates” the pulsar. By accurately measuring the time of passage through periastron
Kyle A. Corcoran +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Globular Cluster Counts around 700 Nearby Galaxies
The Astrophysical JournalEmpirically, the total number (or total mass) of globular clusters (GCs) bound in a single galactic system correlates with the virial mass of the system. The form of this relation and its intrinsic scatter are potentially valuable constraints on theories
Minh Ngoc Le, Andrew P. Cooper
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source