Results 171 to 180 of about 85,801 (378)

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Spectroscopic Confirmation: Fast Rotators in the Young Clusters NGC 1856 and NGC 1953

The Astrophysical Journal
We present the results of a spectroscopic investigation of two Large Magellanic Cloud globular clusters, NGC 1953 and NGC 1856. Both clusters have similar ages (250 and 300 Myr, respectively). Spectra were recorded with the Michigan/Magellan Fiber System
Paul I. Cristofari, Andrea K. Dupree, Antonino P. Milone, Mario Mateo, Matias Chiarpotti   +4 more
doaj   +1 more source

Star-to-Star Abundance Variations among Bright Giants in the Mildly Metal-poor Globular Cluster M4 [PDF]

, 1999
Inese I. Ivans, C. Sneden, Robert P. Kraft, N. B. Suntzeff, Verne V. Smith, G. E. Langer, J. P. Fulbright   +6 more
openalex   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Hot Stars in Globular Clusters

, 1998
26 pages, 11 Postscript figures, to appear in Reviews in Modern Astronomy (Astronomische Gesellschaft)
openaire   +2 more sources

Variable stars in the globular cluster NGC 2419

, 2005
We have used DOLORES at the TNG to obtain B,V time series photometry of NGC 2419, one of the most distant and bright clusters in the Galactic halo. These data will be used to study its variable star population in order to check whether the cluster could be the relic of an extragalactic system accreted by the Milky Way.
Ripepi, V., Greco, C., Baldacci, L., Di Fabrizio, L., Clementini, G., Federici, L., Maio, M., Marconi, M., Musella, I., Stetson, P.   +9 more
openaire   +3 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

New Analyses of Star-to-Star Abundance Variations among Bright Giants in the Mildly Metal-poor Globular Cluster M5 [PDF]

, 2001
Inese I. Ivans, Robert P. Kraft, Christopher Sneden, Graeme H. Smith, R. Michael Rich, Matthew Shetrone   +5 more
openalex   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

New Parameters for Star Cluster Dynamics: The Role of Clusters’ Initial Conditions

The Astrophysical Journal
We recently introduced three new parameters that describe the shape of the normalized cumulative radial distribution (nCRD) of the innermost stars in globular clusters (GCs) and trace the clusters’ dynamical evolution.
B. Bhat, B. Lanzoni, E. Vesperini, F. R. Ferraro, F. I. Aros, A. Askar, A. Hypki   +6 more
doaj   +1 more source