Results 171 to 180 of about 724,005 (372)
Effects of daily alcohol intake on glomerular filtration rate over three years
, 2020 Yu Sato +3 more
openalex +2 more sources
Estimated glomerular filtration rate in a population with normal to mildly reduced renal function as predictor of cardiovascular disease [PDF]
, 2013 Gilad Yahalom +4 more
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis +5 more
wiley +1 more source
Improvement in Renal Function and Reduction in Serum Uric Acid with Intensive Statin Therapy in Older Patients: A Post Hoc Analysis of the SAGE Trial. [PDF]
, 2015 BackgroundImprovement in renal function and decreases in serum uric acid (SUA) have been reported following prolonged high-intensity statin (HMG-CoA reductase inhibitor) therapy.
Deedwania, Prakash C +4 more
core
British Journal of Clinical Pharmacology, EarlyView.Aims To assess the utility of the artificial intelligence (AI) chatbot ChatGPT (openly available version 3.5) in responding to real‐world pharmacotherapeutic queries from healthcare professionals. Methods Three independent and blinded evaluators with different levels of medical expertise and professional experience (beginner, advanced, and expert ...
Benjamin Krichevsky +9 more
wiley +1 more source
Single‐Nephron Glomerular Filtration Rate in Healthy Adults
New England Journal of Medicine, 2017 Aleksandar Denic +8 more
semanticscholar +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Aims To translate a PBPK model developed for the direct oral anticoagulant, dabigatran etexilate, the prodrug of dabigatran, based on data obtained from healthy men to healthy non‐pregnant, pregnant and post‐partum women. To evaluate safety and efficacy of dabigatran etexilate in post‐partum women using simulations and design a future clinical study to
Kayode Ogungbenro +3 more
wiley +1 more source
A real‐world data‐driven approach to optimizing enoxaparin dosing in burn patients
British Journal of Clinical Pharmacology, EarlyView.Aim Enoxaparin dosing in burn patients is challenging due to physiological changes affecting absorption, distribution and clearance. The objectives of this study are to develop a population pharmacokinetic (PK) model for enoxaparin in burn patients, evaluate target attainment with current equation‐based (EQ) dosing and propose an optimized dosing ...
Babajide Shenkoya +3 more
wiley +1 more source