Results 201 to 210 of about 691,066 (375)

Influence of the estimated glomerular filtration rate equation on carboplatin dosing: a real-world study. [PDF]

Front Pharmacol
Fortunato AR, Barbosa C, Araujo A, Fernandez-Llimos F.   +3 more
europepmc   +1 more source

Synthesis of Radioactive Sodium 5-Acetamido-2, 4, 6-triiodo-N-methyl-isophthalamate (¹³¹I) and Its Application to External Measurement of Glomerular Filtration Rate in Rabbits

, 1968
Sadatake Kato, Kunio Kurata, Takao Wakabayashi, Yoshihiko SUGISAWA   +3 more
openalex   +2 more sources

Use of PopPK and E‐R Analyses toward Explaining Causal Link Between ADAMTS13 in Recombinant vs. Plasma‐Based Therapies and Clinical Effects in cTTP

Clinical Pharmacology &Therapeutics, EarlyView.
Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, potentially life‐threatening condition caused by a deficiency of the blood enzyme ADAMTS13. Until now, ADAMTS13 replacement has been achieved with infusions of plasma or plasma‐based therapies (PBT).
Munjal Patel, Huijuan Xu, Olivier Barriere, Paul Diderichsen, Parth Patwari, Andy Z. X. Zhu, Jean François Marier, Thomas Peyret, Linda T. Wang, Björn Mellgård, Wenping Wang, Indranil Bhattacharya   +11 more
wiley   +1 more source

Relationships of Isolated Nocturnal Hypertension with Glomerular Filtration Rate and Albuminuria. [PDF]

Diseases
Carollo C, Geraci G, Sorce A, Morreale Bubella R, Cirafici E, Ciuppa ME, Evola S, Mulè G.   +7 more
europepmc   +1 more source

A METHOD FOR THE URETERAL CATHETERIZATION AND THE DETERMINATION OF THE GLOMERULAR FILTRATION RATE IN RATS; WITH SOME APPLICATIONS ON THE STUDY OF PARATHYROIDS

, 1962
Mikio Shikita
openalex   +2 more sources

Diagnostic Value of Low-Molecular Mass Proteins in Serum for the Detection of Reduced Glomerular Filtration Rate [PDF]

, 1987
Klaus Jung, J.-H. Schulze, K Sydow, M Pergande, K Precht, G Schreiber   +5 more
openalex   +1 more source

Predicting OCT2/MATEs‐Mediated Drug Interactions in Healthy Volunteers and Patients with Chronic Kidney Disease: Insights from Extended Clearance Concept, Endogenous Biomarkers, and In Vitro Inhibition Studies (Perspectives from the International Transporter Consortium)

Clinical Pharmacology &Therapeutics, EarlyView.
Organic cation transporter (OCT) 2 and multidrug and toxin extrusion (MATE) transporters play significant roles in the renal secretion of organic cations and drug–drug interactions (DDIs). Recent in vitro studies indicate that the Ki values for OCT2 exhibit substrate dependency and increase in potency with pre‐incubation.
Satoshi Asano, Aleksandra Galetin, Yoshiko Tomita, Kathleen M. Giacomini, Xiaoyan Chu, Xinning Yang, Toshimichi Nakamura, Hiroyuki Kusuhara, Yuichi Sugiyama   +8 more
wiley   +1 more source

Importance of Creatinine Generation Rate in Estimating Glomerular Filtration Rate. [PDF]

Cureus
Nguyen MK, Bandaru D.
europepmc   +1 more source

Population Pharmacokinetic/Toxicodynamic Model for Polymyxin B in Critically Ill Patients to Identify the Risk of Nephrotoxicity

Clinical Pharmacology &Therapeutics, EarlyView.
Polymyxins are used against highly resistant Gram‐negative pathogens, and nephrotoxicity (acute kidney injury, AKI) is the major dose‐limiting adverse effect. We aimed to develop a well‐informed population pharmacokinetic/toxicodynamic (PK/TD) model using the largest polymyxin B‐treated critically ill patient population studied to inform polymyxin B ...
Patrick O. Hanafin, Ramya Mahadevan, Gauri G. Rao, Alexandre P. Zavascki, Ana Maria Sandri, Andrea Kwa, Marc H. Scheetz, Christine J. Kubin, Jayesh Shah, Benjamin P.Z. Cherng, Michael T. Yin, Jiping Wang, Lu Wang, David P. Calfee, Maureen Bolon, Anthony W. Purcell, Roger L. Nation, Jason M. Pogue, Jian Li, Keith S. Kaye   +19 more
wiley   +1 more source

Current Status of Standardization of Glomerular Filtration Rate Markers in Korea. [PDF]

Ann Lab Med
Jeong TD.
europepmc   +1 more source