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Glomerular filtration barrier

Current Opinion in Nephrology and Hypertension, 2009
In 2008, more than 376 papers were published on the glomerular barrier. Most of them dealt with the podocyte and its role in kidney disease.There is new information on signaling pathways that are utilized in podocytes during proteinuria. Interestingly, the glomerular endothelium, with its fenestrae and glycocalyx, seems to be important for the ...
Börje Haraldsson, Marie Jeansson
openaire   +3 more sources

Assessing kidney function--measured and estimated glomerular filtration rate.

New England Journal of Medicine, 2006
In the coming years, estimates of the glomerular filtration rate (GFR) may replace the measurement of serum creatinine as the primary tool for the assessment of kidney function.
L. Stevens   +3 more
semanticscholar   +1 more source

Discrepancy in calculated and measured glomerular filtration rates in patients treated with PARP inhibitors

International Journal of Gynecological Cancer, 2019
Objective To describe discrepancies in calculated and measured glomerular filtration rate in patients using PARP (poly ADP ribose polymerase) inhibitors who had an elevation in serum creatinine levels.
G. Zibetti Dal Molin   +5 more
semanticscholar   +1 more source

Measurement of Glomerular Filtration Rate

Seminars in Nuclear Medicine, 2022
Glomerular filtration rate (GFR) can be estimated from the plasma concentration of endogenous substances such as creatinine, and it is simple and cost-effective to do so, but the error on these estimates on an individual patient basis is high. Thus, GFR measurement is indicated in any clinical situation in which greater accuracy is required especially ...
James Warwick, Jennifer Holness
openaire   +2 more sources

The Ultrastructure of Glomerular Filtration

Annual Review of Medicine, 1979
The glomeruli of the kidney serve to separate about one third of the plasma entering them into a virtually ideal ultrafiltrate. To accomplish this, fluid is driven by hydraulic forces across the glomerular capillary wall (GCW), which has a high permeability to water but virtually excludes molecules larger than albumin from the filtrate. In recent years
openaire   +3 more sources

Disorders of Glomerular Filtration

1986
In the first edition of this volume, this chapter dealing with disorders of glomerular filtration described, by necessity, few specific mechanisms of altered glomerular ultrafiltration, because the stage of development of this field of investigation was in a rather early phase of data accumulation.
Roland C. Blantz, Juan C. Pelayo
openaire   +2 more sources

Hormonal Regulation of Glomerular Filtration

Annual Review of Medicine, 1985
Technological advances within the last decade now permit examination of the effects of various vasoactive substances on glomerular hemodynamics and the filtration process. By modulating the vasomotor tone of the preglomerular and postglomerular arterioles, these substances influence the rate of plasma entering the glomerulus and the pressure within the
I Ichikawa, V Kon
openaire   +3 more sources

Determinants of the glomerular filtration of proteins

American Journal of Physiology-Renal Physiology, 1981
We showed previously that a theoretical model treating the glomerular capillary wall as a membrane with uniformly distributed fixed negative charges can account for the observed filtration rates of charged derivatives of dextran in the rat. Using measurements of electrophoretic mobility to estimate effective molecular charge, a necessary input ...
William M. Deen, B. Satvat
openaire   +3 more sources

Estimated glomerular filtration rate

BMJ, 2014
What should you do when confronted with a patient with previously unrecognised moderate chronic kidney disease?
Philly O’Riordan   +2 more
openaire   +3 more sources

Glomerular Filtration

2012
Publisher Summary This chapter describes the elementary processes found in nephron and glomerular filtration. The first step in the formation of urine is the formation of an ultrafiltrate of plasma by the renal corpuscle. Ultrafiltration, reabsorption, and secretion constitute the three elementary functions of the nephron. Glomerular filtration is the
openaire   +2 more sources

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