Information, 2019 Statistical bivariate numerical modeling is a method to infer an empirical relationship between unpaired sets of data based on statistical distributions matching.
Sebastian Nicolas Giles, Simone Fiori
doaj +1 more source
Comparing Results of Five Glomerular Filtration Rate-Estimating Equations in the Korean General Population. MDRD Study, Revised Lund-Malmö, and Three CKD-EPI Equations [PDF]
, 2016 Estimated glomerular filtration rate (eGFR) is a widely used index of kidney function. Recently, new formulas such as the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations or the Lund-Malmö equation were introduced for assessing eGFR.
Han-Ik Cho +8 more
core +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2020 Objectives. This study sought to compare the estimated glomerular filtration rate and the indication of dose adjustment of antimicrobials when using Cockcroft-Gault or Modification of Diet in Renal Disease. Methods.
Marianne Silveira Camargo +6 more
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Postnatal maturation of the glomerular filtration rate in conventional growing piglets as potential juvenile animal model for preclinical pharmaceutical research [PDF]
, 2017 Adequate animal models are required to study the preclinical pharmacokinetics (PK), pharmacodynamics (PD) and safety of drugs in the pediatric subpopulation.
Croubels, Siska +8 more
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Urinary proteomics for prediction of mortality in patients with type 2 diabetes and microalbuminuria [PDF]
, 2018 Background: The urinary proteomic classifier CKD273 has shown promise for prediction of progressive diabetic nephropathy (DN). Whether it is also a determinant of mortality and cardiovascular disease in patients with microalbuminuria (MA) is unknown.
Currie, Gemma E. +11 more
core +5 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundThe role of kidney hypoxia is considered pivotal in the progression of chronic kidney disease. A widely used method to assess kidney oxygenation is blood oxygen level dependent (BOLD)–magnetic resonance imaging (MRI), but its interpretation ...
René van der Bel +7 more
doaj +1 more source
Estimated glomerular filtration rate correlates poorly with four-hour creatinine clearance in critically ill patients with acute kidney injury. [PDF]
, 2013 Introduction. RIFLE and AKIN provide a standardised classification of acute kidney injury (AKI), but their categorical rather than continuous nature restricts their use to a research tool. A more accurate real-time description of renal function in AKI is
Kirwan, CJ, Macphee, IA, Philips, BJ
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Diabetic Kidney Disease, Endothelial Damage, and Podocyte-Endothelial Crosstalk
Kidney Medicine, 2021 Diabetes-related complications are a significant source of morbidity and mortality worldwide. Diabetic kidney disease is a frequent microvascular complication and a primary cause of kidney failure in patients with diabetes.
Cindy Lora Gil +2 more
doaj
Tubular secretion of creatinine and kidney function: an observational study. [PDF]
, 2020 BackgroundPrior papers have been inconsistent regarding how much creatinine clearance (CrCl) overestimates glomerular filtration rate (GFR). A recent cross-sectional study suggested that measurement error alone could entirely account for the longstanding
Hsu, Chi-Yuan +5 more
core
A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier
Nature Communications, 2019 In this work we model the glomerular filtration barrier, the structure responsible for filtering the blood and preventing the loss of proteins, using human podocytes and glomerular endothelial cells seeded into microfluidic chips.
Astgik Petrosyan +8 more
semanticscholar +1 more source