Results 41 to 50 of about 691,066 (375)

Renin-angiotensin system antagonists, glomerular filtration rate and blood pressure

Počki, 2018
The article deals with the mModern data on the influence of renin-angiotensin system blockers on the glomerular filtration rate, the level of arterial pressure and the outcome of chronic kidney disease.
D.D. Ivanov
doaj   +1 more source

Renal Hyperfiltration and the Development of Microalbuminuria in Type 1 Diabetes [PDF]

, 2009
OBJECTIVE: The purpose of this study was to examine prospectively whether renal hyperfiltration is associated with the development of microalbuminuria in patients with type 1 diabetes, after taking into account known risk factors.
Aschengrau, Ann, Ficociello, Linda H., Krolewski, Andrzej S., Perkins, Bruce A., Roshan, Bijan, Warram, James H., Weinberg, Janice M.   +6 more
core   +3 more sources

Glomerular filtration in single nephrons

Kidney International, 1972
In recent years as many investigators have turned their attention to the study of tubular transport processes in individual nephrons, it has become increasingly important to measure and to understand the factors that determine the filtration rate of single nephrons (SNGFR).More frequent measurements of SNGFR have yielded a great deal of new information
F. S. Wright, Gerhard Giebisch
openaire   +3 more sources

An in vitro model of the glomerular capillary wall using electrospun collagen nanofibres in a bioartificial composite basement membrane.

PLoS ONE, 2011
The filtering unit of the kidney, the glomerulus, contains capillaries whose walls function as a biological sieve, the glomerular filtration barrier.
Sadie C Slater, Vince Beachley, Thomas Hayes, Daming Zhang, Gavin I Welsh, Moin A Saleem, Peter W Mathieson, Xuejun Wen, Bo Su, Simon C Satchell   +9 more
doaj   +1 more source

Elevation of Trimethylamine-N-Oxide in Chronic Kidney Disease: Contribution of Decreased Glomerular Filtration Rate

Toxins, 2019
Gut microbiota-dependent Trimethylamine-N-oxide (TMAO) has been reported to be strongly linked to renal function and to increased cardiovascular events in the general population and in Chronic Kidney Disease (CKD) patients.
Caroline C. Pelletier, Mikaël Croyal, L. Ene, A. Aguesse, S. Billon-Crossouard, M. Krempf, S. Lemoine, F. Guebre-egziabher, L. Juillard, C. Soulage   +9 more
semanticscholar   +1 more source

Impairment in Glomerular Filtration Rate or Glomerular Filtration Barrier and Occurrence of Stroke [PDF]

Archives of Neurology, 2008
Chronic kidney disease (CKD) is associated with substantial burden and is a strong risk factor for cardiovascular disease. However, data on the relationship between CKD and stroke are few and are limited by unreliable or inadequate assessment of renal function.To properly assess the relationship between renal insufficiency and stroke in stroke ...
openaire   +3 more sources

Effect of sex on glomerular filtration rate in programmed rats by prenatal dexamethasone

Physiological Reports, 2019
We have previously demonstrated that dexamethasone administered to pregnant rats during specific times during gestation results in a reduction in glomerular number and hypertension in offspring at 2 and 6 months of age.
Jyoti Jain, Susan K. Legan, Issa Alhamoud, Jyothsna Gattineni, Michel Baum   +4 more
doaj   +1 more source

Renal hyperfiltration defined by high estimated glomerular filtration rate: A risk factor for cardiovascular disease and mortality

Diabetes, obesity and metabolism, 2019
Renal hyperfiltration, defined as an increased glomerular filtration rate above normal values, is associated with early phases of kidney disease in the setting of various conditions such as obesity and diabetes.
M. Kanbay, Lale A. Ertuglu, B. Afşar, E. Ozdoğan, Zeynep S. Kucuksumer, A. Ortiz, A. Covic, M. Kuwabara, D. Cherney, D. V. van Raalte, D. de Zeeuw   +10 more
semanticscholar   +1 more source

Co-Culture of Glomerular Endothelial Cells and Podocytes in a Custom-Designed Glomerulus-on-a-Chip Model Improves the Filtration Barrier Integrity and Affects the Glomerular Cell Phenotype

Biosensors, 2023
Crosstalk between glomerular endothelial cells and glomerular epithelial cells (podocytes) is increasingly becoming apparent as a crucial mechanism to maintain the integrity of the glomerular filtration barrier.
Daan C. ‘t Hart, Dilemin Yildiz, Valentina Palacio-Castañeda, Lanhui Li, Burcu Gumuscu, Roland Brock, Wouter P. R. Verdurmen, Johan van der Vlag, Tom Nijenhuis   +8 more
doaj   +1 more source

Abemaciclib Inhibits Renal Tubular Secretion Without Changing Glomerular Filtration Rate

Clinical pharmacology and therapy, 2018
Abemaciclib, an inhibitor of cyclin dependent kinases 4 and 6, is indicated for metastatic breast cancer treatment. Reversible increases in serum creatinine levels of ~15–40% over baseline have been observed following abemaciclib dosing.
J. Chappell, P. Turner, Y. A. Pak, J. Bacon, A. Chiang, J. Royalty, Stephen D. Hall, P. Kulanthaivel, J. Bonventre   +8 more
semanticscholar   +1 more source