Results 91 to 100 of about 416,019 (379)
Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines
Advanced Science, EarlyView.This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li +11 more
wiley +1 more source
Clinics, 2014 OBJECTIVE:Pneumoperitoneum during laparoscopy results in transient oliguria and decreased glomerular filtration and renal blood flow. The presence of oliguria and elevated serum creatinine is suggestive of acute renal injury.
Rodrigo Moreira e Lima +6 more
doaj +1 more source
Journal of the American Medical Association (JAMA), 2015 IMPORTANCE Because early-stage kidney disease is asymptomatic and is associated with both morbidity and mortality, laboratory measurements are required for its detection.
A. Levey, Cassandra Becker, L. Inker
semanticscholar +1 more source
Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition
Advanced Science, EarlyView.Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu +12 more
wiley +1 more source
Effect of sex on glomerular filtration rate in programmed rats by prenatal dexamethasone
Physiological Reports, 2019 We have previously demonstrated that dexamethasone administered to pregnant rats during specific times during gestation results in a reduction in glomerular number and hypertension in offspring at 2 and 6 months of age.
Jyoti Jain +4 more
doaj +1 more source
Acute effect of prednisolone on renal handling of sodium. [PDF]
, 1973 The effect of prednisolone on renal handling of sodium (Na) was studied in rats under three experimental conditions: 1) hydropenia, 2) water diuresis, and 3) distal tubular blockade (DTB).
Halgrimson, CG +3 more
core +1 more source
Advanced Science, EarlyView.Prevention and treatment of diabetic kidney disease (DKD) have become a major global public health challenge. This study shed new light on the underlying pathogenic mechanisms of podocyte injury in DKD and highlights the therapeutic potential of mitigating podocyte injury through inhibition of the RIPK3/NF‐κB p65‐mediated inflammatory response as a ...
Lu'an Li +10 more
wiley +1 more source
DIABETIC KIDNEY DISEASE: DEFINITION, DIAGNOSIS, DIFFERENT PROGRESSIVE STAGES, CLASSIFICATION
Revista de la Sociedad Argentina de Diabetes, 2018 Chronic kidney disease (CKD) is classified according to the cause, the stage of glomerular filtration and albuminuria. Diabetic kidney disease (DKD) according to the classification of glomerular filtration (GF) and the quantification of albuminuria.
María Estela Canda
doaj +1 more source
Estimated glomerular filtration rate in patients overdosed with gentamicin
Journal of Laboratory Medicine, 2020 The aim of this study was to compare the estimated glomerular filtration rate (eGFR) from serum creatinine (eGFRcrea) and cystatin C (eGFRcys) in patients with elevated serum trough levels of gentamicin before the next planned dose during treatment in ...
Šálek Tomáš +2 more
doaj +1 more source
TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis [PDF]
, 2014 Severe sepsis is often accompanied by acute kidney injury (AKI) and albuminuria. Here we studied whether the AKI and albuminuria associated with lipopolysaccharide (LPS) treatment in mice reflects impairment of the glomerular endothelium with its ...
Alper, Seth L. +5 more
core +2 more sources