Results 201 to 210 of about 416,019 (379)

Folinic Acid Prophylaxis and Dose Adjustments Enable Safe Treatment with Pemetrexed in Patients with Renal Impairment

Clinical Pharmacology &Therapeutics, EarlyView.
Pemetrexed is a cornerstone in chemo(immunotherapy) of non‐small cell lung cancer and mesothelioma; however, it is contraindicated in patients with renal impairment due to severe toxicity concerns. Therefore, a large proportion of patients is withheld from effective chemo(immunotherapy).
Nikki de Rouw, Leila‐Sophie Otten, Mart P. Kicken, Berber Piet, Bonne Biesma, Bianca van Veggel, Christi M.J. Steendam, Ben van den Borne, Lizza E.L. Hendriks, Sander Croes, Anne‐Marie C. Dingemans, Daphne W. Dumoulin, Ron H.J. Mathijssen, Jacobus A. Burgers, Alwin D.R. Huitema, Hieronymus J. Derijks, Maarten J. Deenen, Michel M. van den Heuvel, Rob ter Heine   +18 more
wiley   +1 more source

Relationships of Isolated Nocturnal Hypertension with Glomerular Filtration Rate and Albuminuria. [PDF]

Diseases
Carollo C, Geraci G, Sorce A, Morreale Bubella R, Cirafici E, Ciuppa ME, Evola S, Mulè G.   +7 more
europepmc   +1 more source

Measurement of glomerular filtration rate utilizing a single subcutaneous injection of 125I-iothalamate

, 1973
Arnold H. Israelit, Dewey L. Long, Martin White, Alan R. Hull   +3 more
openalex   +1 more source

Poor renal uptake of technetium-99m-DMSA and technetium-99m-MDP in a patient with Fanconi syndrome and near normal glomerular filtration rate [PDF]

, 1994
Sang Eun Kim, Jong Tae Cho, Dong Soo Lee, June Key Chung, Suhnggwon Kim, Myung Chul Lee, Jung Sang Lee, Chang Soon Koh   +7 more
openalex   +1 more source

Microbiome‐Informed Dosing: Exploring Gut Microbial Communities Impact on Mycophenolate Enterohepatic Circulation and Therapeutic Target Achievement

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacomicrobiomics is an emerging field due to important microbiome effects on pharmacokinetics and clinical outcomes. However, the application of this knowledge remains limited. Mycophenolic acid (MPA) is the primary active metabolite of the immunosuppressant, mycophenolate mofetil (MMF).
Abdelrahman Saqr, Shen Cheng, Mahmoud Al‐Kofahi, Christopher Staley, Pamala A. Jacobson   +4 more
wiley   +1 more source

Importance of Creatinine Generation Rate in Estimating Glomerular Filtration Rate. [PDF]

Cureus
Nguyen MK, Bandaru D.
europepmc   +1 more source

Measurement of residual glomerular filtration rate in the patient receiving repetitive hemodialysis

, 1975
Jovan Milutinovic, Ralph E. Cutler, Patricia Hoover, Barbara Meijsen, Belding H. Scribner   +4 more
openalex   +1 more source

Comparison of Regression and Categorical Analysis for Pharmacokinetic Data From Renal Impairment Studies

Clinical Pharmacology &Therapeutics, EarlyView.
The US Food and Drug Administration 2024 guidance prefers regression analysis over categorical analysis for pharmacokinetic data for studies that assess pharmacokinetics in patients with impaired renal functions. The objective of this study was to compare these two statistical methods for pharmacokinetic data analysis of renal impairment studies ...
Gerald Chun‐To So, Ying Grace Li, Stephen D. Hall, Jenny Chien, Christopher D. Payne, Maria M. Posada, Maria Lucia Buziqui Piruzeli, Yan Jin   +7 more
wiley   +1 more source

Current Status of Standardization of Glomerular Filtration Rate Markers in Korea. [PDF]

Ann Lab Med
Jeong TD.
europepmc   +1 more source

Captopril-induced fall in glomerular filtration rate in cyclosporine-treated hypertensive patients. [PDF]

, 1993
J J Curtis, David A. Laskow, Patsy Jones, Bruce A. Julian, Robert S. Gaston, Robert Luke   +5 more
openalex   +1 more source