Results 91 to 100 of about 17,810 (305)

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

A comparative evaluation of disinfection effect of exposures to ultra-violet light and direct current glow discharge on Candida Albicans colonies coated over elastomeric impression material: An in vitro study

Journal of Pharmacy and Bioallied Sciences, 2013
Aim: The aim of our study is to compare the efficacy of ultra-violet light (U-V light) and direct current glow discharge in disinfecting Candida Albicans coated elastomeric impression material.
Vijay Anand
doaj   +1 more source

Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor

Advanced Science, EarlyView.
The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao, Dongdong Liu, Haishan Gao, Chenyang Qin, Wen Zhang, Ziyun Lu, Dongxia Tan, Yuxiu Qu, Yusong Liu, Zhiran Zou, Hongtao Yu, Wei Qi   +11 more
wiley   +1 more source

Non-Self-Sustained Atmospheric Pressure Glow Discharges Maintained by the DC Helium Glow Discharge [PDF]

, 2009
International audienceThe possibilities of obtaining large-volume non-self-sustained atmospheric pressure glow discharge with the help of the self-sustained normal dc glow discharge in helium are demonstrated.
Arkhipenko, V.I., Callegari, Thierry, Kirillov, A.A, Safronau, Ya.A.   +3 more
core   +1 more source

A Conserved DT2‐bZIP66‐NF‐YC4 Regulatory Module Confers Drought Tolerance in Rice and Arabidopsis

Advanced Science, EarlyView.
This study identifies a conserved tripartiteDT2–bZIP66–NF‐YC4 transcriptional module that enhances rice drought tolerance by activating stress‐responsive genes. This regulatory complex is functionally conserved across cereals and Arabidopsis, providing promising targets for engineering drought‐resilient crops. ABSTRACT Drought stress severely restricts
Jun Shen, Yuchen Li, Liang Zhang, Xiaosong Ma, Chenyin Peng, Chunting Yuan, Yu Wu, Kaiyu Zhao, Sheng Zhao, Jiazhuo Guo, Run Li, Ziqian Yan, Shule Ren, Yige Han, Xin Lin, Xinyue Li, Ming Li, Pingfang Yang, Shiyong Song   +18 more
wiley   +1 more source

Numerical methods and time-dependent physical models for the design and diagnostic of pulsed-dc magnetrons [PDF]

, 2006
Pulsed DC operation of magnetrons is a relatively new sputtering technique that significantly improves the properties of deposited layers. The understanding and control of phenomena taking place during pulsed DC sputtering requires new time-resolved ...
Moiseev, Tamara
core  

The concept of plasma cleaning in glow discharge spectrometry [PDF]

, 2009
A plasma cleaning procedure to improve elemental depth profiling of shallow layered materials by glow discharge spectrometry is proposed. The procedure is based on two approaches applied prior to depth profiling, either individually or sequentially.
Bordel, Nerea, Malherbe, J., Guillot, Philippe, Skeldon, P., Hohl, M., Thompson, G. E., Bordel, N., Nelis, T., Nelis, Thomas, Ganciu, Mihai, Therese, L., Belenguer, Philippe, Zahri, Abdellatif, Tempez, A., Molchan, I. S., Lobo Revilla, L., Zahri, A., Trigoulet, N., Belenguer, Ph, Ganciu, M., Chapon, P., Guillot, Ph, Michler, J., Therese, Laurent P.   +23 more
core   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Investigation the effect of operating conditions on Te and ne of Argon plasma glow discharge at cathode graphite

Journal of Kufa-Physics, 2019
In this study, the spectral analysis technique was used to calculate the electron temperature and density of argon gas using the ratio method between the two spectral lines.
Abdulhussain A. khadayeir, Falah H. yousif   +1 more
doaj   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source