Results 131 to 140 of about 31,440 (256)

GLP-1 receptor agonists and their implications for female reproductive health. [PDF]

Case Rep Womens Health
Eagles E, Simpson B, Makajeva J, Ayuk PT.   +3 more
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

GLP-1 Receptor Agonists in Brazil: Landscape of Consumption, Safety and Regulation. [PDF]

Diabetes Obes Metab
Hurtado RL, Amato AA, de Luca Corrêa H, Silveira D.   +3 more
europepmc   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Are GLP-1 receptor agonists a 'magic bullet' for cancer? [PDF]

Nat Rev Cancer
Hebert JR, Murphy EA, Playdon MC, Makowski L, Ibele AR, Fairman CM, Hofseth LJ.   +6 more
europepmc   +1 more source

Glucagon‐like peptide‐1 receptor agonists and muscle strength changes in older adults: Risks beyond muscle mass reductions

British Journal of Pharmacology, EarlyView.
Abstract Gastric inhibitory polypeptide (GIP)/Glucagon‐like peptide‐1 (GLP‐1) receptor agonists are increasingly prescribed for the management of obesity and type 2 diabetes, yet research pertinent to their effects on muscle health is limited. Considering the central role of muscle strength as a sarcopenia component, this article summarizes emerging ...
Konstantinos Prokopidis
wiley   +1 more source

The Potential Indirect Impact of GLP-1 Receptor Agonists in the Management of Fibromyalgia. [PDF]

J Clin Med
Quodling N, Carrick FR, Hoffman N, Jemni M.   +3 more
europepmc   +1 more source

Experimental peptides, GLP‐1s and polypharmacy: Future directions for image‐ and performance‐enhancing drug harm reduction

Addiction, EarlyView.
Luke A. Turnock, Lambros Lazuras
wiley   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

British Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

Interpreting Pregnancy Risk After GLP-1 Receptor Agonists Discontinuation. [PDF]

Diabetes Obes Metab
Scairati R, Newman C, Dunne FP, Colao A.
europepmc   +1 more source